Herbicidal sulfonamides

ABSTRACT

This invention relates to certain sulfonylurea compounds having substituents ortho to the sulfonylurea linkage that includes a 3- or 4- membered carbocyclic ring, a saturated 5- or 6- membered carbocyclic ring or a heterocyclic ring which contains 1 heteroatom selected from O, S and NR 3 , agriculturally suitable compositions thereof and a method of their use as herbicides or plant growth regulants.

RELATED APPLICATIONS

This is a continuation-in-part of application U.S. Ser. No. 680,549 filed Dec. 11, 1984, now abandoned.

BACKGROUND OF THE INVENTION

This invention relates to herbicidally active sulfonylurea compounds, agriculturally suitable compositions containing them and their method of use as herbicides or plant growth regulants.

In the most common situation, the control of undesired vegetation is desired to permit the growth of useful crops such as cotton, rice, corn, wheat and soybeans, to name a few. Unchecked weed growth in such useful crops can cause significant losses, reducing profit to the farmer and increasing costs to the consumer. In other situations, herbicides are desired which will control all plant growth. Examples of areas in which the complete control of all vegetation is desired are areas around fuel storage tanks, ammunition depots and industrial storage areas. There are many products commercially available for these purposes, but the search continues for products which are more effective, less costly and environmentally safe.

Euporean Patent Application (EP-A) No. 83,975, published July 20, 1983, discloses herbicidal benzenesulfonamides of formula ##STR1## wherein Q is selected from various five or six-membered aromatic or partially unsaturated heterocyclic rings containing 2 or 3 heteroatoms selected from O, S or NR.

U.S. Pat. No. 4,368,069 discloses herbicidal benzenesulfonamides of formula ##STR2## wherein R is --(CR₅ R₆)_(n) --R₂ ;

n is 0 or 1; and

R₂ may be C₂ -C₅ alkenyl, C₅ -C₆ cycloalkenyl or C₂ -C₃ alkenyl substituted with 1-3 chlorine atoms.

European Patent Application (EP-A) No. 85,476, published Aug. 10, 1983, discloses herbicidal benzenesulfonamides of formulae ##STR3## wherein Q is selected from various 5-membered aromatic heterocycles, and their dihydro and tetrahydro analogs, which contain one heteroatom selected from O, S or NR, or Q is a saturated or partially unsaturated 6-membered ring containing one heteroatom selected from O or S; and

Q¹ is a 6-membered aromatic heterocycle containing one to three N atoms.

South African Patent Application 83/8416, published May, 1984, discloses herbicidal benzenesulfonamides of formula ##STR4## wherein A is an unsaturated or only partially saturated 5- or 6-membered heterocyclic ring system which is bonded through a carbon atom and contains 1, 2 or 3 heteroatoms.

Herbicidal thiophene sulfonamides are disclosed in European Patent Application (EP-A) Nos. 30,142, published June 10, 1981, and 97,122, published Dec. 28, 1983, and in U.S. Pat. Nos. 4,127,405, 4,169,719, 4,398,939 and 4,441,910.

No. EP-A-95,925, published Dec. 7, 1983, discloses herbicidal pyrazolesulfonamides in which the group adjacent to the sulfonamide moiety may be selected from H, C₁ -C₃ alkyl, F, Cl, Br, NO₂, OR₁₆, CO₂ R₂₃, S(O)_(n) R₂₄ or SO₂ NR₁₉ R₂₀.

No. EP-A-87,780, published Sept. 7, 1983 discloses pyrazole sulfonamides of general formula ##STR5## wherein A is H, C₁ -C₈ alkyl or optionally substituted phenyl;

B and C are independently H, halogen, NO₂, C₁ -C₈ alkyl, CO₂ R, etc.; and

D is H or C₁ -C₈ alkyl.

No. EP-A-96,003, published Nov. 28, 1983, discloses herbicidal compounds of general formul ##STR6## wherein R₁ is H or C₁ -C₃ alkyl; and

Q is an unsubstituted or substituted five-membered heterocyclic radical which is bound by way of a carbon atom and which contains 2 or 3 identical or different heteroatoms.

Herbicidal pyridinesulfonamides are disclosed in European Patent Application (EP-A) Nos. 13,480 published July 23, 1980, 35,893 published Sept. 16, 1981, 97,122 published Dec. 28, 1983 and 103,543 published Mar. 21, 1984 and in U.S. Pat. No. 4,435,206.

U.S. Pat. No. 4,420,325 discloses herbicidal sulfonamides of the following formula ##STR7## wherein R₁ is F, Cl, Br, CF₃, C₁ -C₃ alkoxy, C₁ -C₃ alkyl, NO₂, CO₂ R₄, SO₂ R₅, SO₂ NR₆ R₇, SO₂ N(OCH₃)CH₃, SO₂ OCH₂ CF₃, OSO₂ R₅ or CH₂ L;

R₂ is H, Cl, Br, F, CF₃ or OCH₃ ;

R₉ is H or C₁ -C₃ alkyl; etc.

SUMMARY OF THE INVENTION

This invention is the discovery of new compounds with herbicidal activity, agriculturally suitable compositions thereof and a method of using said compounds as general or selective preemergent and/or post emergent herbicides. Accordingly the new compounds of the invention are compounds of the formula ##STR8## wherein W is O or S;

R is H or CH₃ ;

L is ##STR9## n is 0 or 1; R₁ is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, nitro, CN, C₁ -C₃ alkoxy, SO₂ NR^(I) R^(II), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, CO₂ R^(III), CH₂ CN, CH₂ OCH₃ or CH₂ SCH₃ ;

R^(I) is H, C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy or ethoxy;

R^(II) is H, C₁ -C₄ alkyl or C₃ -C₄ alkenyl; or

R^(I) and R^(II) may be taken together as --(CH₂)₃ --, --(CH₂)₄ --, --(CH₂)₅ -- or --CH₂ CH₂ OCH₂ CH₂ --;

R^(III) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ haloalkyl, C₂ -C₃ cyanoalkyl, C₅ -C₆ cycloalkyl, C₄ -C₇ cycloalkylalkyl or C₂ -C₄ alkoxyalkyl;

R₂ is C₁ -C₃ alkyl;

Q is a 3- or 4-membered heterocyclic ring which contains one heteroatom selected from O, S and NR₃, or a 3- or 4-membered carbocyclic ring in which one carbon atom may optionally be in the form of a carbonyl group, or a fully-saturated 5- or 6-membered carbocyclic ring, and Q may be optionally substituted with 1-4 substituents selected from halogen, CN, OH, C₁ -C₃ alkyl, C₁ -C₃ alkoxy, C₁ -C₃ alkylthio, C₂ -C₄ alkoxycarbonyl, C₁ -C₄ alkylsulfonyl, (C₁ -C₄ alkyl)aminosulfamyl and di(C₁ -C₄ alkyl)aminosulfamoyl;

R₃ is C₁ -C₄ alkyl;

R₁₂ is H or OR₁₄ ;

R₁₃ is H or C₁ -C₄ alkyl;

R₁₄ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ haloalkenyl, C₃ -C₄ alkynyl, C₃ -C₄ haloalkynyl, C₂ -C₄ alkylcarbonyl, C(O)NR₁₅ R₁₆, C₁ -C₄ alkylsulfonyl, C₂ -C₄ alkoxyalkyl or C₂ -C₄ alkylthioalkyl;

R₁₅ and R₁₆ are independently H or C₁ -C₂ alkyl;

A is ##STR10## X is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, halogen, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino or di(C₁ -C₃ alkyl)amino;

Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, C₁ -C₄ haloalkyl, C₃ -C₅ cycloalkyl, C₂ -C₄ alkynyl, ##STR11## or or N(OCH₃)CH₃ ; m is 2 or 3;

L₁ and L₂ are independently O or S;

R₄ and R₅ are independently C₁ -C₂ alkyl;

R₆ is H or CH₃ ;

Z is CH or N;

Y₁ is O or CH₂ ;

X₁ is CH₃, OCH₃, OC₂ H₅ or OCF₂ H;

Y₂ is H or CH₃ ;

X₂ is CH₃, OCH₃ or SCH₃ ;

Y₃ is CH₃, CH₂ CH₃ or CH₂ CF₃ ;

X₃ is CH₃ or OCH₃ ;

Y₄ is CH₃, OCH₃, OC₂ H₅ or Cl; and

X₄ is CH₃, OCH₃, OC₂ H₅ or CH₂ OCH₃ ;

and their agriculturally suitable salts; provided that

(a) when X is Cl, F, Br or I, then Z is CH and Y is OCH₃, OC₂ H₅, N(OCH₃)CH₃, NHCH₃, N(CH₃)₂ or OCF₂ H;

(b) when X or Y is OCF₂ H, then Z is CH;

(c) when L is L-2 or L-3, then the Q substituent and the sulfonylurea bridge are on adjacent carbon atoms;

(d) when W is S, then R is H, A is A-1, and Y is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃ or CH(OCH₃)₂ ;

(e) the total number of carbon atoms of R₁₂ and R₁₃ must be less than or equal to four; and

(f) when the total number of carbon atoms of X and Y is greater than four, then the number of carbons of R₁ must be less than or equal to two and the number of carbons of Q must be less than or equal to six.

In the above definitions, the term "alkyl," used either alone or in compound words such as "alkylthio" or "haloalkyl," denotes straight or branched alkyl, e.g. methyl, ethyl, n-propyl, isopropyl or the different butyl isomers.

Alkoxy denotes methoxy, ethoxy, n-propoxy, isopropoxy and the different butoxy isomers.

Alkenyl denotes straight chain or branched alkenes, e.g. vinyl, 1-propenyl, 2-propenyl, 3-propenyl and the different butenyl isomers.

Alkynyl denotes straight chain or branched alkynes, e.g. ethynyl, 1-propynyl, 2-propynyl and the different butynyl isomers.

Cycloalkyl denotes cyclopropyl, cyclobutyl, cyclopentyl and cyclohexyl.

The term "halogen," either alone or in compound words such as "haloalkyl," denotes fluorine, chlorine, bromine and iodine.

In terms such as C₂ -C₃ alkylthioalkyl, the specified number of carbon atoms is meant to define the total number of carbon atoms in that substituent group. For example, C₂ -C₃ alkylthioalkyl would designate CH₂ SCH₃, CH₂ SC₂ H₅, CH₂ CH₂ SCH₃ or CH(CH₃)SCH₃, and C₂ -C₅ alkoxyalkoxy would represent OCH₂ OCH₃ through O(CH₂)₄ OCH₃ or OCH₂ O(CH₂)₃ CH₃ and the various structural isomers embraced therein.

Alkoxycarbonyl denotes methoxycarbonyl, ethoxycarbonyl, propoxycarbonyl and isopropoxycarbonyl.

Alkylcarbonyl denotes e.g. acetyl, propionyl, and the different butyryl isomers.

Alkylsulfonyl denotes methylsulfonyl, ethylsulfonyl and the different propylsulfonyl and butylsulfonyl isomers.

Alkylthio, alkylsulfinyl, alkylamino, alkylsulfamoyl etc. are defined in an analogous manner.

The compounds of the invention which are preferred for reasons of increased ease of synthesis and/or greater herbicidal efficacy are:

(1) Compounds of Formula I where Q is ##STR12## wherein R₃ is C₁ -C₃ alkyl;

R₇ is H, F, Cl, Br, CN, CH₃ or OCH₃ ;

R₈ is H, F, Cl, Br, I, CN, OH, C₁ -C₃ alkyl, C₁ -C₃ alkoxy, C₂ -C₃ alkoxycarbonyl, di(C₁ -C₃ alkyl)aminosulfamoyl, C₁ -C₃ alkylthio or C₁ -C₃ alkylsulfonyl;

R₉ and R₁₀ are independently H, CH₃, F, Cl or may be taken together to form C═O; and

R₁₁ is H or C₁ -C₃ alkyl;

provided that

(a) when R₇ and R₈ are attached to the same carbon atoms as in Q-1, Q-2 or Q-3, or in Q-4 through Q-10, and R₇ is OCH₃, then R₈ is other than F, Cl, Br, I or OH; and

(b) when R₇ and R₈ are attached to the same carbon atom as in Q-1, Q-2 or Q-3, or in Q-4 through Q-10, and R₈ is F, Cl, Br, I or OH, then R₇ is other than OCH₃.

(2) Compounds of Preferred 1 where

A is A-1,

W is O; and

R is H.

(3) Compounds of Preferred 2 where

R₁ is selected from H, F, Cl, NO₂, C₁ -C₂ alkyl, C₁ -C₂ haloalkyl, C₁ -C₂ alkoxy, C₁ -C₂ alkylthio, CH₂ OCH₃ or CH₂ SCH₃ ;

R₁₃ is H or CH₃ ;

R₁₄ is H, C₁ -C₂ alkyl, CH₂ CH═CH₂ or CH₂ C.tbd.CH;

X is CH₃, OCH₃, OC₂ H₅, Cl, F, Br, OCF₂ H, CH₂ F, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂, CF₃, CH₂ Cl or CH₂ Br; and

Y is H, C₁ -C₃ alkyl, OCH₃, OC₂ H₅, CH₂ OCH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OC₂ H₅, OCH₂ CH₂ OCH₃, CH₂ SCH₃, OCF₂ H, SCF₂ H, cyclopropyl, C.tbd.CH or C.tbd.CCH₃.

(4) Compounds of Preferred 3 where

L is L-1; and

Q is Q-1, Q-2 or Q-4.

(5) Compounds of Preferred 4 where Q is Q-1;

(6) Compounds of Preferred 5 where

R₁ is H, Cl, CH₃, OCH₃ or SCH₃ and is not in the 4-position;

R₇ is H, F, Cl, CH₃ or OCH₃ ;

R₈ is H, F, Cl, CH₃ or OCH₃ ; and

R₉ and R₁₀ are independently H, CH₃, F or Cl.

(7) Compounds of Preferred 3 where

L is L-2 or L-3; and

Q is Q-1, Q-2 or Q-4.

(8) Compounds of Preferred 7 where

R₁ is H;

R₇ is H, F, Cl, CH₃ or OCH₃ ;

R₈ is H, F, Cl, CH₃ or OCH₃ ;

R₉ and R₁₀ are independently H, CH₃, F or Cl; and

R₁₁ is H or CH₃.

(9) Compounds of Preferred 3 where

L is L-4 or L-5; and

Q is Q-1, Q-2 or Q-4.

(10) Compounds of Preffered 9 where

R₁ is H;

R₇ is H, F, Cl, CH₃ or OCH₃ ;

R₈ is H, F, Cl, CH₃ or OCH₃ ;

R₉ and R₁₀ are independently H, CH₃, F or Cl; and

R₁₁ is H or CH₃.

(11) Compounds of Preferred 3 where

L is L-6; and

Q is Q-1, Q-2 or Q-4.

(12) Compounds of Preferred 11 where

R₁ is H;

R₇ is H, F, Cl, CH₃ or OCH₃ ;

R₈ is H, F, Cl, CH₃ or OCH₃ ;

R₉ and R₁₀ are independently H, CH₃, F or Cl; and

R₁₁ is H or CH₃.

The compounds of the invention which are specifically preferred for reasons of their expected greatest ease of synthesis and/or greatest herbicidal efficacy are:

2-(2,2-dichlorocyclopropyl)-N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]benzenesulfonamide, m.p. 193°-195° C.;

2-(2,2-dichlorocyclopropyl)-N-[(4-methoxy-6-methyl)aminocarbonyl]benzenesulfonamide, m.p. 168°-170° C.; and

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranylmethyl)benzenesulfonamide, m.p. 157°-159° C.(d).

DETAILED DESCRIPTION OF THE INVENTION Synthesis

The compounds of Formula I can be prepared by reacting an appropriate sulfonyl isocyanate or sulfonyl isothiocyanate, II, with an appropriately substituted aminoheterocycle, III, as shown in Equation 1, where R, W, A and L are as previously defined. ##STR13##

The reaction is best performed in an inert solvent such as methylene chloride or toluene at 25° to 100° C., for 1 to 24 hours. Isolation of the product can be achieved by concentrating the solution and trituration with an appropriate solvent such as butyl chloride.

Alternatively, compounds of Formula I, where W is O, can be prepared by reacting the sulfonamides of Formula IV with the carbamates of Formula V (R'═CH₃) in the presence of an excess of trimethylaluminum, as shown in Equation 2, where L, R and A are as previously defined, provided R₁ is other than CO₂ R^(III). ##STR14##

The reactions are best performed in an inert solvent such as methylene chloride at the reflux point of the solution (40° C.) for 10 to 24 hours. Isolation of the product is best achieved by exposing the reaction mixture to acetic acid, separation of the layers and concentrating the organic layer to a solid.

Alternatively, compounds of Formula I can be prepared by exposing a phenyl carbamate V (R'═Ph) to the sulfonamide IV in an appropriate solvent such as dioxane at 25° to 100° C. in the presence of a strong base such as 1,8-diazabicyclo[5.4.0]undec-7-ene; acid workup affords the desired product, as disclosed in European Patent Application (EP-A) 44,807. Compounds of Formula I can also be prepared from a phenyl carbamate V and the tert-butyldimethylsilyl-protected sulfonamide IV (LSO₂ NHSi(CH₃)₂ -t-Bu). Addition of tetrabutylammonium fluoride to a mixture of the carbamate and sulfonamide affords after workup the desired product. The required carbamates can be prepared from the corresponding amines, III, and dimethyl or diphenylcarbonate or methyl or phenylchloroformate and a base such as sodium hydride.

The sulfonyl isocyanates, II, used in the preparation of I are known in the art and can be prepared by known methods. For example, isocyanates can be prepared by exposing an appropriate benzene or heterocyclic sulfonamide to phosgene in the presence of an alkyl isocyanate and an amine catalyst such as 1,4-diazabicyclo[2.2.2]octane at the reflux point of the solvent; see H. Ulrich and A. A. Y. Sayigh, Newer Methods of Preparative Organic Chemistry, Vol. VI, p. 223-241, Academic Press, New York and London, W. Forest Ed.

The sulfonyl isothiocyanates, II, used in the preparation of I, where W is S, can be prepared according to the procedure of K. Hartke, Arch. Pharm., 299, 174 (1966).

Sulfonamides of Formula L-1 (compound 3) where Q is Q-1, n=0, R₁, and R₇ through R₁₀ are as previously defined can be prepared in one or more of the ways outlined in Equations 3 through 7. ##STR15##

The addition of carbenes to styrene is well known in the art. For further details of such transformations see Keller, W. E., "Compendium of Phase-Transfer Reactions and Related Synthetic Methods", Fluka A. G., Switzerland, p 39-64, 1979. ##STR16##

An alternate sequence, outlined below in Equation 5, can be employed in selected cases where lithiation of 2 may be a problem due to functional group incompatibility with n-BuLi, (i.e., R₇ =CO₂ CH₃). ##STR17##

The sulfonamide 3 can also be prepared by direct alkylation with the preformed cyclopropyl methyl halide 8 as outlined in Equation 6. ##STR18##

For further details pertaining to this modification of the Ullmann reaction see, S. Gronowitz, and S. Lilgefors, Chemica Scripta, 13, 157-161 (1978-79) and A. Minato, K. Tamo, T. Hayasi, K. Suzuki and M. Kumada; Tetrahedron Letters, 22, 5319 (1981).

In Equation 5 the dihaloethane 9 may be replaced with other electrophiles such as propylene oxide and its derivatives, as shown in Equation 7. ##STR19##

The ortho-lithiation of compounds such as 1, 2, 5 and 5a is well known to those skilled in the art. For further details pertaining to this type of transformation see Meyers, A. I., Michlich, B. D., and Nolan, R. L., J. Org. Chem., 39, 2783, 1974.

Sulfonamides of Formula L-1 (Compound 12) where n is 1, Q is Q-1 through Q-3 and R₁, R₃ and R₇ through R₁₃ are as previously defined can be prepared in a similar manner to that already described in Equations 3, 4 and 6, with slight modifications of the starting material. For example cyclopropanation of the styrene homolog 13, followed by ortho-lithiation chemistry would afford the target Compound 12 as outlined in Equation 8. ##STR20##

In an analogous manner to Equation 6, cyclopropane 12 can be prepared as outlined in Equation 9. ##STR21##

Alternatively, sulfonamide 12 can be prepared by a modified Ullmann reaction utilizing sulfonamide 5 as the starting material as outlined in Equation 10. ##STR22##

The epoxy sulfonamides of Formula L-1 (Compound 15) where Q is Q-2 and n, R₁, R₇, R₈ and R₁₁ are as previously defined can be prepared directly from olefins 1, 4 and 13 via epoxidation using m-chloroperbenzoic acid as described in Equation 11. ##STR23##

Further details pertaining to olefin epoxidations may be found in Org. Syn., Coll. Vol. 1, 494 (1944).

The aziridine sulfonamides where Q is Q-3 and n, R₁, R₃, R₇, R₈ and R₁₁ are as previously defined such as compound 16 can also be prepared from the corresponding olefins using the procedure outlined in Equation 12. ##STR24##

For further details see Gebelein, C. O., Swift, G., Swern, D., J. Org. Chem., 32, 3314 (1967).

Sulfonamides of Formula L-2, L-3, L-4, L-5 and L-6, where Q is Q-1 through Q-3 and n, R₁, R₂, R₃ and R₇ through R₁₁ are as previously defined can be prepared using one or more of the routes previously outlined in Equations 3 through 12.

For example, in the case of L-3, sulfonamide 18 can be prepared using the same route described in Equation 3 or 4. This is outlined in Equation 13. ##STR25##

Sulfonamides (such as 20) containing a four-membered ring where R₁, R₇ and R₈ are as previously defined may be prepared in one or more of the ways outlined in Equations 14 through 17b. ##STR26##

For a discussion of photochemical 2+2 cycloadditions of styrene with olefins, aldehydes and ketones (the Paterno-Buchi reaction) see Silversmith, Kitahara, Caserio and Roberts, J. Am. Chem. Soc., 80, 5840 (1958).

An alternate synthesis of compounds such as 20 is via the anionic ring closure of chloride 25 as outlined in Equation 16. ##STR27##

In a similar manner the oxetane ring systems can be formed as shown in Equation 17a and 17b. ##STR28##

The methodology described in Equations 15, 17a and 17b can also be used to prepare the thio and amine analogs, that is sulfonamides of Formula L-1 where Q is Q-7 through Q-10 and R₁, R₃, R₇ and R₈ are as previously defined, and n=0 (i.e., 29 and 30). ##STR29##

Examples of anionic four membered ring closures may be found in Corey, E. J. and Seebach, D., Org. Synth., 50, 72 (1970).

Sulfonamides of Formula L-2, L-3, L-4, L-5 and L-6 where Q is Q-4 through Q-10 and R, R₁, R₂, R₃, R₇ and R₈ are as previously defined can be prepared in a similar manner to that already taught for L-1 in Equations 14 through 17b utilizing the appropriate starting sulfonamides (e.g. 19) as described previously.

In the case where n is 1 the corresponding sulfonamides such as 31 and 32 can be prepared by the procedures outlined in Equation 18a and 18b. ##STR30##

Sulfonamide 34 where R₁₂ is OH, R₁₃ is H (n=1) can be prepared as outlined in Equation 19. ##STR31##

The use of the tert-butyldimethylsilyl group allows for low temperature generation of the anion and mild removal of the protecting group. In the same manner alkylation of 36 with ketones such as cyclobutanone allows for the preparation of sulfonamide 37 as outlined in Equation 20. ##STR32##

Preparation of a heterocyclic sulfonamide wherein R₁₂ is H and R₁₃ is OH (n=1) is accomplished in the same way as already taught for an aromatic system in Equations 19 and 20. For example, sulfonamide 38 can be prepared from protected pyrazole sulfonamide 39 as outlined in Equation 21. ##STR33##

Sulfonamides such as 34 or 38 can be used to prepare sulfonamides such as 40. Generation of the alkoxide with sodium hydride followed by the addition of the appropriate alkylating group affords protected alcohols such as 40. ##STR34##

An alternate preparation of protected alcohols, for example 41, is to trap directly the incipient lithium alkoxide (42) resulting from the condensation of the anion of 36 with aldehydes and ketones. This is depicted in Equation 23. ##STR35##

For further information pertaining to the synthesis of pyrazole sulfonamides see: No. EP-A-95,925; for thiophene sulfonamides, No. EP-A-30,142; for pyridine sulfonamides, No. EP-A-13,480, and benzyl sulfonamides, No. EP-A-51,466 and U.S. Pat. No. 4,420,325.

The heterocyclic amines of Formula III can be prepared by methods known in the literature or simple modifications thereof, by those skilled in the art. For instance, No. EP-A-84,224 (published July 27, 1983) and W. Braker et al, J. Am. Chem. Soc. 1947, 69, 3072 describe methods for preparing aminopyrimidines and triazines substituted by acetal groups. Also, South African Patent Application Nos. 825,045 and 825,671 describe methods for preparing aminopyrimidines and triazines substituted by haloalkyl or haloalkylthio groups such as OCH₂ CH₂ F, OCH₂ CF₃, SCF₂ H, and OCF₂ H among other groups. South African Patent Application No. 837,434 (published Oct. 5, 1983) describes methods for the synthesis of cyclopropylpyrimidines and triazines substituted by such groups as alkyl, haloalkyl, alkoxy, haloalkoxy, alkylamino, dialkylamino, and alkoxyalkyl.

The 5,6-dihydrofuro[2.3-d]pyrimidin-2-amines, and the cyclopenta[d]pyrimidin-2-amines, of formula III, wherein A is A-2, and the 6,7-dihydro-5H-pyrano[2.3-d]pyrimidin-2-amines, of formula III, where A is A-3, can be prepared as described in EP-A No. 15,863. The furo[2.3-d]pyrimidin-2-amines, of formula III, where A is A-4, are described in EP-A No. 46,677. Heterocycles of formula III, where A is A-5, may be prepared as described in EP-A No. 73,562. Heterocycles of Formula III, where A is A-6, may be prepared by methods taught in No. EP-A-94,260.

In addition, general methods for preparing aminopyrimidines and triazines have been reviewed in the following publications.

"The Chemistry of Heterocyclic Compounds", a series published by Interscience Publishers, Inc., New York and London;

"Pyrimidines", Vol. 16 of the same series by D. J. Brown;

"s-Triazines and Derivatives", Vol. 13 of the same series by E. M. Smolin and L. Rapaport; and

F. C. Schaefer, U.S. Pat. No. 3,154,547 and K. R. Huffman and F. C. Schaefer, J. Org. Chem., 28, 1812 (1963), which describe the synthesis of triazines.

Agriculturally suitable salts of compounds of Formula I are also useful herbicides and can be prepared in a number of ways known to the art. For example, metal salts can be made by contacting compounds of Formula I with a solution of an alkali or alkaline earth metal salt having a sufficiently basic anion (e.g., hydroxide, alkoxide or carbonate). Quaternary amine salts can be made by similar techniques.

Salts of compounds of Formula I can also be prepared by exchange of one cation for another. Cationic exchange can be effected by direct contacting of an aqueous solution of a salt of a compound of Formula I (e.g., alkali metal or quaternary amine salt) with a solution containing the cation to be exchanged. This method is most effective when the desired salt containing the exchanged cation is insoluble in water, e.g., a copper salt, and can be separated by filtration.

Exchange may also be effected by passing an aqueous solution of a salt of a compound of Formula I (e.g., an alkali metal or quaternary amine salt) through a column packed with a cation exchange resin containing the cation to be exchanged. In this method, the cation of the resin is exchanged for that of the original salt and the desired product is eluted from the column. This method is particularly useful when the desired salt is water-soluble, e.g., a potassium, sodium or calcium salt.

Acid addition salts, useful in this invention, can be obtained by reacting a compound of Formula I with a suitable acid, e.g., p-toluenesulfonic acid, trichloroacetic acid or the like.

The preparation of the compounds of this invention is illustrated by the following examples.

EXAMPLE 1 Preparation of 2-Ethenylbenzenesulfonamide

2-Bromostyrene (10.0 g, 54.9 mmol) was added dropwise to n-BuLi in 250 ml of tetrahydrofuran at -78° C. After stirring for 15 minutes the solution was added via a cannula to a solution of sulfurylchloride fluoride (9.7 g, 82.4 mmol) in 50 ml of tetrahydrofuran cooled to -78° C. The reaction mixture was quenched with brine and separated. The organic layer was dried and concentrated to approximately half-volume. This solution was added to anhydrous ammonia (100 ml) cooled to -78° C. The reaction was warmed to room temperature, excess ammonia was removed and the solids were filtered off. The filtrate was concentrated and the resulting oil was triturated with butyl chloride and ethyl acetate to yield the desired sulfonamide, m.p. 103°-105° C.

EXAMPLE 2 Preparation of 2-(2-Oxiranyl)benzenesulfonamide

A solution consisting of 2-ethenebenzenesulfonamide (1.5 g, 8.1 mmol) m-chloroperbenzoic acid (1.4 g, 8.1 mmol) and potassium carbonate (1.1 g, 8.1 mmol) in 150 ml of chloroform was stirred for 4 days at room temperature. The reaction was filtered and the filtrate was washed with saturated sodium bicarbonate. The organic layer was separated, dried and concentrated. The resulting oil was flash chromatographed (methylene chloride) to yield the subject compound as a white solid, m.p. 136°-139° C.

EXAMPLE 3 Preparation of 1-Bromo-2-(2,2-Dichlorocyclopropyl)benzene

A 20 ml solution of 50% sodium hydroxide was added dropwise to 2-bromostyrene (10.0 g, 54.9 mmol) in 100 ml of chloroform. The reaction mixture was warmed to 45° C. for 1 hour. After cooling the solution was separated and the organic layer was dried over magnesium sulfate and concentrated. The resulting liquid was flash chromatographed, affording 11.6 g of the desired compound.

EXAMPLE 4 Preparation of N-[(4,6-Dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranyl)benzenesulfonamide

To a stirring solution of the 2-(2-oxiranyl)benzenesulfonamide (75 mg, 0.376 mmol) and 4,6-dimethoxy-2-aminophenoxycarbonyl pyrimidine (103 mg, 0.37 mmol) in 5 ml of acetonitrile was added 1,8-diazabicyclo[5.4.0]undec-7-ene (57 mg, 0.37 mmol). The reaction was stirred for 3 hours followed by quenching with 3 ml of 5% hydrochloric acid. The solution was diluted with ethyl acetate, separated and dried. The organics were concentrated to yield 140 mg of the desired product, m.p. 177°-179° C.; NMR (200 MHz, CDCl₃)δ: 2.3 (dd, 1H); 3.1 (dd, 1H); 3.95 (s, 6H); 4.7 (dd, 1H); 5.88 (s, 1H); 7.0 (br s, 1H); 7.55 (m, 3H) and 8.2 (dd, 1H).

EXAMPLE 5 Preparation 2-(2,2-Dichlorocyclopropyl)-N-[(4-methoxy-6-methylpyrimidin-2-yl)aminocarbonyl]benzenesulfonamide

To a stirring solution of 2-(2,2-dichlorocyclopropyl)benzenesulfonamide (200 mg, 0.75 mmol) and 4-methyl-6-methoxy-2-aminophenoxycarbonyl pyrimidine (195 mg, 0.75 mmol) was added diazobicycloundecane (115 mg, 0.75 mmol). Work-up as described in Example 5 afforded 180 mg of the desired compound, m.p. 187°-191° C.; NMR (200 MHz, CDCl₃)δ: 2.05 (dd, 2H); 2.41 (s, 3H); 3.79 (dd, 1H); 3.94 (s, 3H); 6.27 (s, 1H); 7.2 (d, 1H); 7.57 (m, 3H) and 8.4 (dd, 1H).

EXAMPLE 6 2-[(Cyclopropyl)(hydroxy)methyl]-N-[(dimethyl((1,1-dimethylethyl)silyl]benzenesulfonamide

To a stirring solution of n-BuLi (5.2 g, 80.8 mmol) in 300 ml of THF cooled to -10° C. was added dropwise tert-butyldimethylsilylbenzenesulfonamide (10.0 g, 36.7 mmol) in 25 ml of THF. The solution was stirred for one hour. After cooling to -78° C., cyclopropyl aldehyde (2.8 g, 40.0 mmol) was added. The reaction mixture was stirred for 30 minutes, then quenched with brine. The organic layer was separated, dried over magnesium sulfate and concentrated in vacuo. Flash chromatography (20% EtOAc:hexane, v/v) afforded 2.7 g of the desired product as a viscous oil; NMR (200 MHz, CDCl₃): δ 0.24 (d, 6H), 0.4 (m, 1H), 0.45-0.8 (m, 3H), 0.88 (s, 9H)), 1.6 (m, 1H), 2.85 (d, 1H), 4.9 (dd, 1H), 5.30 (s, 1H), 5.67 (brs, 1H), 7.41 (t, 1H), 7.54 (t, 1H), 7.76 (d, 1H), 7.98 (d, 1H).

EXAMPLE 7 N-[(4,6-Dimethylpyrimidin-2-yl)aminocarbonyl]-2-(1-hydroxycyclobutyl)benzenesulfonamide

To a mixture of the phenylcarbamate of 4,6-dimethyl-2-aminopyrimidine (178 mg, 0.73 mmol) and tert-butyldimethylsilane-protected 2-(1-hydroxycyclobutane)benzenesulfonamide in 5 ml of acetonitrile was added tetrabutylammonium fluoride (231 mg, 0.73 mmol). The reaction mixture was stirred for 5 minutes followed by the addition of 5% HCl. The resulting solids were collected and dried to give 250 mg of the desired product; m.p. 148°-150° C.; NMR (200 MHz, CDCl₃); δ 2.45 (s, 7H), 2.58 (m, 5H), 6.76 (s, 1H), 7.47-7.75 (m, 4H), 8.32 (d, 1H).

    ______________________________________                                         TABLE of STRUCTURES                                                            ______________________________________                                         General Structure I                                                             ##STR36##                                                                     where W is O unless otherwise indicated by *,                                  where W is S.                                                                  For ring systems Q-4 through Q-10, the substituents                            R.sub.7 and R.sub.8 are attached as follows                                     ##STR37##                                                                     General Structure II                                                            ##STR38##                                                                      ##STR39##                                                                      ##STR40##                                                                     For ring systems Q-4 through Q-10, the substituents                            R.sub.7 and R.sub.8 are attached as follows                                     ##STR41##                                                                     General Structure IIa                                                           ##STR42##                                                                      ##STR43##                                                                      ##STR44##                                                                     General Structure IIb                                                           ##STR45##                                                                      ##STR46##                                                                      ##STR47##                                                                     General Structure III                                                           ##STR48##                                                                     General Structure IV                                                            ##STR49##                                                                     L-2 and L-3 are as in                                                          General Structure II.                                                          n = 0                                                                          General Structure V                                                             ##STR50##                                                                     L-2 and L-3 are as in                                                          General Structure II,                                                          R.sub.9 and R.sub.10 are C O                                                   n = 0                                                                          ______________________________________                                    

                                      TABLE I                                      __________________________________________________________________________     General structure I (wherein R.sub.12 and R.sub.13 are H)                      Q  n R  R.sub.1                                                                          R.sub.7                                                                             R.sub.8                                                                               R.sub.9                                                                           R.sub.10                                                                           R.sub.11                                                                          X     Y     Z   m.p. (°C.)              __________________________________________________________________________     Q-1                                                                               0 H  H H    H      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH  197-198.5                      Q-1                                                                               0 H  H H    H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH  209-210                        Q-1                                                                               0 H  H H    H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH  202-204                        Q-1                                                                               0 CH.sub.3                                                                          H H    H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N   144-146                        Q-1                                                                               0 H  H H    H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N   190-191                        Q-1                                                                               0 H  H H    H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N   174-176                        Q-1                                                                               0 H  H H    H      H  H   -- Cl    OCH.sub.3                                                                            CH  192-194                        Q-1                                                                               0 H  H H    F      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    F      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H H    F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH  174-177                        Q-1                                                                               0 H  H H    Cl     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N   172-175                        Q-1                                                                               0 H  H Cl   H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH  186-188                        Q-1                                                                               0 H  H Cl   H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N   156-160                        Q-1                                                                               0 H  H H    Br     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Br   H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    I      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H H    H      H  H   -- NHCH.sub.3                                                                           OCH.sub.2 CH.sub.3                                                                   N   203-206                        Q-1                                                                               0 H  H H    CN     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CN   H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH  155-159                        Q-1                                                                               0 H  H H    CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH  180-182                        Q-1                                                                               0 H  H H    CH.sub.3                                                                              H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH  215-216                        Q-1                                                                               0 H  H CH.sub.3                                                                            H      H  H   -- Cl    OCH.sub.3                                                                            N   175-176                        Q-1                                                                               0 H  H CH.sub.3                                                                            H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N   154-157                        Q-1                                                                               0 H  H H    CH.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.2 CH.sub.3                                                                   H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.2 CH.sub.2 CH.sub.3                                                            H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    Cl     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH  182-185                        Q-1                                                                               0 H  H H    Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N   139-142                        Q-1                                                                               0 H  H H    Cl     H  H   -- Cl    OCH.sub.3                                                                            CH  185-187                        Q-1                                                                               0 H  H H    Cl     H  H   -- OCH.sub.2 CH.sub.3                                                                   NHCH.sub.3                                                                           CH  154-158                        Q-1                                                                               0 H  H H    Br        CH.sub.3                                                                           -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    Br     H  Cl  -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    Br     H  F   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H H    Br     H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    Br     H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    Br     H  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    I      H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CN     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CN     H  CH.sub. 3                                                                          -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CN     H  Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    CN     H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CN     H  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CN     CH.sub.3                                                                          H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H H    OCH.sub.3                                                                             H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    OCH.sub.3                                                                             H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    OCH.sub.3                                                                             H  Cl  -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    OCH.sub.3                                                                             Cl H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    OCH.sub.3                                                                             F  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    OCH.sub.3                                                                             H  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SO.sub.2 N(CH.sub.3).sub.2                                                            H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SO.sub.2 N(CH.sub.3).sub.2                                                            H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SO.sub.2 N(CH.sub.3).sub.2                                                            H  F   -- CH.sub.3                                                                             OCH   CH                                 Q-1                                                                               0 H  H H    SO.sub.2 N(CH.sub.3).sub.2                                                            H  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SO.sub.2 N(CH.sub.3).sub.2                                                            H  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SCH.sub.3                                                                             H  CH.sub.3                                                                           -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SCH.sub.3                                                                             H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SCH.sub.3                                                                             H  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    OCH.sub.3                                                                             H  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    OCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H CH.sub.3 O                                                                          H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    OCH.sub.2                                                                             H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CO.sub. 2 CH.sub.3                                                                    H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CO.sub.2 CH.sub.2 CH.sub.3                                                            H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SO.sub.2 N(CH.sub.3).sub.2                                                            H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SO.sub.2 N(CH.sub.3).sub.2                                                            H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    SCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.2 CH.sub.3                                                            H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CH.sub.3                                                                              H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CH.sub.3                                                                              CH.sub.3                                                                          H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CH.sub.3                                                                              H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CH.sub.3                                                                              Br H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    F      H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    F      H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    Cl     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    Cl     H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    Cl     H  Cl  -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    Cl     H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    Cl     H  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    SO.sub.2 CH.sub.3                                                                     H  Br  -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H F    F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    F      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H F    F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H F    F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H F    F      H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Cl     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH  187-191                        Q-1                                                                               0 H  H Cl   Cl     H  H   -- OCH.sub.3                                                                            OCH.sub. 3                                                                           CH  193-195                        Q-1                                                                               0 H  H Cl   Cl     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N   168-170                        Q-1                                                                               0 H  H Cl   Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N   190-193                        Q-1                                                                               0 H  H Cl   Cl     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH  233-235                        Q-1                                                                               0 H  H Cl   Cl     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N   195-199                        Q-1                                                                               0 H  H Cl   Cl     H  H   -- Cl    OCH.sub.3                                                                            CH  199-202                        Q-1                                                                               0 H  H Br   Br     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   Br     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   Br     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   Br     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   Br     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Br   Br     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H I    I      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CN   CN     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H CN   CN     H  H   -- OCH.sub.3                                                                            CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  H   -- Cl    OCH.sub.3                                                                            CH  154-156                        Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH   N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N   152-155                        Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH  179-180                        Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H F    F      H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H F    F      H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    F      H  Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H F    F      H  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   Cl     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub. 3                                                                           N                                  Q-1                                                                               0 H  H Cl   Cl     H  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Cl     H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Cl     H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   Cl     H  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   Br     H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Br   Br     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   Br     H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   Br     H  Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H Br   Br     Cl H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   Br     H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   Br     H  Br  -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3                                                                          H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  CH.sub. 3                                                                          -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CO.sub.2 CH.sub.3                                                                   CO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    F      CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    F      CH.sub.3                                                                          CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    F      F  F   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H F    F      F  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H F    F      F  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H F    F      Cl Cl  -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    F      Cl Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    F      Br Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    F      Br Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   Cl     CH.sub.3                                                                          CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   Cl     CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Cl   Cl     CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Cl     F  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Cl     F  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   Cl     Cl Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   Cl     Cl Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Cl     Br Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Cl     Br Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H I    I      CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CN   CN     CH.sub.3                                                                          CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     CH.sub.3                                                                          CH.sub.3                                                                           -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     F  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H CN   CN     F  F   -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H CN   CN     F  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CN     Cl Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H CN   CN     Br Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CN   CN     Br Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              F  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              Cl Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              Cl Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              Cl Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              Br Br  -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CH.sub.3                                                                              Br Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             CH.sub.3                                                                          CH.sub.3                                                                           -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             Cl Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             F  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             F  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             F  F   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             Br Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             Br Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    Cl     H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    Br     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    CH.sub.3                                                                              H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    CN     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H F    CH.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H F    OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H F    CO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    SO.sub.2 N(CH.sub.3).sub.2                                                            H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    SCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H F    SO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   F      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Cl   F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Br     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   CN     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   CH.sub.3                                                                              H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Cl   OCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Cl   CO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   SO.sub.2 N(CH.sub.3).sub.2                                                            H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H Cl   SCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   SO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   Cl     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Br   Cl     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   Br     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   CN     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H Br   CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   CH.sub.3                                                                              H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   CH.sub.3                                                                              H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   CH.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   OCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H Br   CO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Br   SO.sub.2 N(CH.sub.3 ).sub.2                                                           H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   SCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   SO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H I    F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H I    Cl     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H I    Br     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H I    CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CN   Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CN   Br     H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   CH.sub.3                                                                              H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CN   CH.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H CN   CO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H CN   SCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   SO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H H    F      F  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    F      F  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    F      Cl Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    F      Br F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              F  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CH.sub.3                                                                              F  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CH.sub.3                                                                              F  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              Br CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              Cl CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    Cl     F  Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               0 H  H H    Cl     F  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    Cl     Br Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    Cl     F  CH.sub.3                                                                           -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CN     F  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CN     F  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CN     F  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CN     Cl CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CN     Cl Br  -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              F  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              F  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              F  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CH.sub.3                                                                              Cl Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    CH.sub.3                                                                              Cl Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.3                                                                              Br CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.2 CH.sub.3                                                                     F  Cl.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    CH.sub.2 CH.sub.2 CH.sub.3                                                            F  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    OCH.sub.3                                                                             F  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    OCH.sub.3                                                                             F  Br  -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H H    OCH.sub.3                                                                             F  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H H    OCH.sub.3                                                                             Cl Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    Cl     F  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H F    Cl     F  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H F    Br     Cl CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Cl   CH.sub.3                                                                              CH.sub.3                                                                          F   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               0 H  H Br   OCH.sub.3                                                                             CH.sub.3                                                                          F   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H SCH.sub.3                                                                           CO.sub.2 CH.sub.3                                                                     F  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Br   Cl     F  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H Br   I      F  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               0 H  H CH.sub.3                                                                            CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                          Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Br     Cl Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H Cl   Br     Cl CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H I    F      F  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   F      F  Cl  -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               0 H  H CN   Br     Cl CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    H      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H H    H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    H      H  H   -- OCH.sub. 3                                                                           OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    H      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H H    H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    H      H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    F      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H H    F      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H H    F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    Cl     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H Cl   H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    Br     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H Br   H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    I      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H I    H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    CN     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CN   H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H H    CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    CH.sub.3                                                                              H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            H      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            H      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    CH.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    CH.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    CH.sub.2 CH.sub.2 CH.sub.3                                                            H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H H    OCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H CH.sub.3 O                                                                          H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    OCH.sub.2 CH.sub.3                                                                    H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H H    CO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    CO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    CO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    CO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    CO.sub.2 CH.sub.2 CH.sub.3                                                            H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    SO.sub.2 N(CH.sub.3).sub.2                                                            H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    SO.sub.2 N(CH.sub.3).sub.2                                                            H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H H    SCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    SCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H SO.sub.2 CH.sub.3                                                                   H      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.2 CH.sub.3                                                            H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    CH.sub.3                                                                              H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    CH.sub.3                                                                              H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    CH.sub.3                                                                              CH.sub.3                                                                          H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H H    CH.sub.3                                                                              H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    CH.sub.3                                                                              H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    CH.sub.3                                                                              H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    CH.sub.3                                                                              H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    CH.sub.3                                                                              Br H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    F      H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    F      H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    Cl     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    Cl     H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    Cl     H  Cl  -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    Cl     H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    Cl     H  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                           -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H H    SO.sub.2 CH.sub.3                                                                     H  Br  -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H F    F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H F    F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H F    F      H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H F    F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H F    F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H F    F      H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   Cl     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   Cl     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Cl   Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Cl   Cl     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H Cl   Cl     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H Cl   Cl     H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   Br     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   Br     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   Br     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   Br     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   Br     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H I    I      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   CN     H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   CN     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CN   CN     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H F    F      H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H F    F      H  CH.sub.3                                                                           -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H F    F      H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H F    F      H  Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H F    F      H  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Cl   Cl     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Cl   Cl     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   Cl     H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   Cl     H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Cl   Cl     H  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   Br     H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H Br   Br     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   Br     H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   Br     H  Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H Br   Br     Cl H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   Br     H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   Br     H  Br  -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   CN     H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   CN     H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   CN     H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3                                                                          H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              H  Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  CH.sub.3                                                                           -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             H  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CN   CN     CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H CN   CN     F  F   -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H CN   CN     F  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   CN     Cl Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H CN   CN     Br Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CN   CN     Br Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              F  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              Cl Cl  -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              Cl Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              Cl Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              Br Br  -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.3                                                                              Br Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             CH.sub.3                                                                          CH.sub.3                                                                           -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             CH.sub.3                                                                          CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             Cl Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             F  F   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             F  F   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             F  F   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H OCH.sub.3                                                                           OCH.sub.3                                                                             Br Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H Cl   OCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H Cl   CO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   SO.sub.2 N(CH.sub.3).sub.2                                                            H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H Cl   SCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Cl   SO.sub.2 CH.sub.3                                                                     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   Cl     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H Br   Cl     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   Br     H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   CN     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-1                                                                               1 H  H Br   CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   CH.sub.3                                                                              H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   CH.sub.3                                                                              H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   CH.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   OCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   OCH.sub.3                                                                             H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   OCH.sub.2 CH.sub.3                                                                    H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   CO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-1                                                                               1 H  H Br   SO.sub.2 N(CH.sub.3).sub.2                                                            H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   SCH.sub.3                                                                             H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   SO.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H I    F      H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H I    Cl     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H I    Br     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H I    CH.sub.3                                                                              H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   F      H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CN   Cl     H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   Br     H  H   -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   CH.sub.3                                                                              H  H   -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CN   CH.sub.2 CH.sub.3                                                                     H  H   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H F    Cl     F  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H F    Cl     F  CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H F    Br     Cl CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Cl   CH.sub.3                                                                              CH.sub.3                                                                          F   -- CH.sub.3                                                                             CH.sub. 3                                                                            CH                                 Q-1                                                                               1 H  H Br   OCH.sub.3                                                                             CH.sub.3                                                                          F   -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Br   Cl     F  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H Br   I      F  Cl  -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H CH.sub.3                                                                            CH.sub.2 CH.sub.3                                                                     CH.sub.3                                                                          Br  -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   Br     Cl Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H Cl   Br     Cl CH.sub.3                                                                           -- CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CO.sub.2 CH.sub.3                                                                   SCH.sub.3                                                                             F  Cl  -- CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-1                                                                               1 H  H I    F      F  Br  -- OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   F      F  Cl  -- Cl    OCH.sub.3                                                                            CH                                 Q-1                                                                               1 H  H CN   Br     Cl CH.sub.3                                                                           -- OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  __________________________________________________________________________     Q  n  R  R.sub.1                                                                              R.sub.7                                                                               R.sub.8                                                                               R.sub.11                                                                             X   Y    Z  m.p. (°C.)               __________________________________________________________________________     Q-2                                                                               0  H  H     H      H      H     CH.sub.3                                                                           CH.sub.3                                                                            CH 158-160                         Q-2                                                                               0  H  H     H      H      H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH 177-179                         Q-2                                                                               0  H  H     H      H      H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     H      H      H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      H      H     Cl  OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      CH.sub.3                                                                              H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      CH.sub.3                                                                              H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      CH.sub.3                                                                              H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      CH.sub.3                                                                              H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      Cl     H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      Cl     H     OCH.sub.3                                                                          CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     H      Cl     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      Cl     H     Cl  OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      F      H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     H      F      H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     H      F      H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     H      F      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      F      H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      F      H     Cl  OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      CN     H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      CN     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      OCH.sub.3                                                                             H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      OCH.sub.3                                                                             H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      OCH.sub.3                                                                             H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      CO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     H      CO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     H      CO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      CO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      CO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     H      CO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      CO.sub.2 CH.sub.3                                                                     H     Cl  OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      SO.sub.2 N(CH.sub.3).sub.2                                                            H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     H      SO.sub.2 N(CH.sub.3).sub.2                                                            H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      SO.sub.2 N(CH.sub.3).sub.2                                                            H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      SO.sub.2 N(CH.sub.3).sub.2                                                            H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      SCH.sub.3                                                                             H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      SCH.sub.3                                                                             H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     H      SCH.sub.3                                                                             H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     H      SCH.sub.3                                                                             H     Cl  OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      SO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     H      SO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      SO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     F      F      H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     F      F      H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     Cl     Cl     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     Cl     Cl     H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     F      Cl     H     OCH.sub.3                                                                          CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     F      CH.sub.3                                                                              H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     CH.sub.3                                                                              CH.sub.3                                                                              H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     CH.sub.3                                                                              CH.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     F      Br     H     Cl  OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     Br     Br     H     Cl  OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     Br     Br     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     CO.sub.2 CH.sub.3                                                                     CO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     CO.sub.2 CH.sub.3                                                                     CO.sub.2 CH.sub.3                                                                     H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     CO.sub.2 CH.sub.3                                                                     CO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     CN     CN     H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     CN     CN     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     CN     CN     H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     OCH.sub.3                                                                             OCH.sub.3                                                                             H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     OCH.sub.2 CH.sub.3                                                                    OCH.sub.2 CH.sub.3                                                                    H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     SCH.sub.3                                                                             SCH.sub.3                                                                             H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     SCH.sub.3                                                                             SCH.sub.3                                                                             H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     SO.sub.2 CH.sub.3                                                                     SO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     SO.sub.2 CH.sub.3                                                                     SO.sub.2 CH.sub.3                                                                     H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     H      H      CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  H     H      H      CH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      H      CH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     H      H      CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               0  H  H     F      H      CH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     Cl     H      CH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  H     F      F      CH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     Br     H      CH.sub.3                                                                             OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  H     Cl     Cl     CH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  5-CH.sub.3                                                                           H      H      --    OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               0  H  5-OCH.sub.3                                                                          H      H      --    CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2                                                                               0  H  5-SCH.sub.3                                                                          H      H      --    CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  5-Cl  Cl     H      --    OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               0  H  6-Cl  F      F      CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               0  CH.sub.3                                                                          H     H      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           N                                  Q-2                                                                               1  H  H     H      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               1  H  H     F      F      H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               1  H  H     F      Cl     H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               1  H  H     CH.sub.3                                                                              Cl     H     OCH.sub.3                                                                          CH.sub.3                                                                            CH                                 Q-2                                                                               1  H  H     F      H      H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               1  H  H     Cl     H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               1  H  H     Br     H      H     CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               1  H  H     Cl     Cl     H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               1  H  H     CH.sub.3                                                                              H      H     CH.sub.3                                                                           OCH.sub.3                                                                           CH                                 Q-2                                                                               1  H  H     CH     H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               1  H  H     CH     CH     H     CH.sub.3                                                                           OCH.sub.3                                                                           N                                  Q-2                                                                               1  H  H     CH.sub.3                                                                              Br     H     CH.sub.3                                                                           CH.sub.3                                                                            CH                                 Q-2                                                                               1  H  H     F      Br     H     Cl  OCH.sub.3                                                                           CH                                 Q-2                                                                               1  H  5-CH.sub.3                                                                           F      H      H     OCH.sub.3                                                                          OCH.sub.3                                                                           CH                                 Q-2                                                                               1  H  5-OCH.sub.3                                                                          Cl     H      CH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                            N                                  Q-2                                                                               1  H  5-Cl  Cl     Cl     CH.sub.2 CH.sub.3                                                                    CH.sub.3                                                                           OCH.sub.3                                                                           N                                  __________________________________________________________________________     Q  n  R  R.sub.1                                                                             R.sub.3                                                                               R.sub.7                                                                            R.sub.8                                                                               R.sub.11                                                                            X   Y   Z  m.p. (°C.)              __________________________________________________________________________     Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CH.sub.3                                                                              H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CH.sub.3                                                                              H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CH.sub.3                                                                              H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CH.sub.3                                                                              H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   Cl     H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   Cl     H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   Cl     H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   Cl     H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   F      H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   F      H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   F      H    OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   F      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   F      H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   F      H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CN     H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CN     H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   OCH.sub.3                                                                             H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   OCH.sub.3                                                                             H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   OCH.sub.3                                                                             H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                     H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                     H    OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                     H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                     H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                     H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                     H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   CO.sub.2 CH.sub.3                                                                     H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SO.sub.2 N(CH.sub.3).sub.2                                                            H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SO.sub.2 N(CH.sub.3).sub.2                                                            H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SO.sub.2 N(CH.sub.3).sub.2                                                            H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SO.sub.2 N(CH.sub.3).sub.2                                                            H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SCH.sub.3                                                                             H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SCH.sub.3                                                                             H    CH.sub.3                                                                           CH.sub.3                                                                           Cl                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SCH.sub.3                                                                             H    OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SCH.sub.3                                                                             H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SO.sub.2 CH.sub.3                                                                     H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SO.sub.2 CH.sub.3                                                                     H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   SO.sub.2 CH.sub.3                                                                     H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              F   F      H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              F   F      H    OCH.sub.3                                                                          CH.sub.3                                                                           Cl                                Q-3                                                                               0  H  H    CH.sub.3                                                                              Cl  Cl     H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              Cl  Cl     H    CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              F   Cl     H    OCH.sub.3                                                                          CH.sub.3                                                                           N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              F   CH.sub.3                                                                              H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.3                                                                              H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              CH.sub.3                                                                           CH.sub.2 CH.sub.3                                                                     H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              F   Br     H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              Br  Br     H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              CN  CN     H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              CN  CN     H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              CN  CN     H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              OCH.sub.3                                                                          OCH.sub.3                                                                             H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      CH.sub.3                                                                            CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      CH.sub.3                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      OCH.sub.3                                                                           OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              H   H      CH.sub.2 CH.sub.3                                                                   OCH.sub.3                                                                          CH.sub.3                                                                           N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              F   H      CH.sub.3                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              Cl  H      CH.sub.3                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  H    CH.sub.3                                                                              F   F      CH.sub.3                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              Br  H      CH.sub.3                                                                            OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  H    CH.sub.3                                                                              Cl  Cl     CH.sub.3                                                                            CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  5-CH.sub.3                                                                          CH.sub.3                                                                              H   H      --   OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  H  6-OCH.sub.3                                                                         CH.sub.3                                                                              H   H      --   CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               0  H  3-SCH.sub.3                                                                         CH.sub.3                                                                              H   H      --   CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  5-Cl CH.sub.3                                                                              Cl  H      --   OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               0  H  6-Cl CH.sub. 2 CH.sub.3                                                                    F   F      CH.sub.3                                                                            CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               0  H  5-OCH.sub.2 F                                                                       CH.sub.2 CH.sub.3                                                                     Cl  H      H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               0  CH.sub.3                                                                          H    CH.sub.2 CH.sub.3                                                                     H   H      H    OCH.sub.3                                                                          OCH.sub.3                                                                          N                                 Q-3                                                                               1  H  H    CH.sub.2 CH.sub.3                                                                     H   H      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               1  H  H    CH.sub.3                                                                              F   F      H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               1  H  H    CH.sub.3                                                                              F   Cl     H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               1  H  H    CH.sub.2 CH.sub.3 CH.sub.3                                                            CH.sub.3                                                                           Cl     H    OCH.sub.3                                                                          CH.sub.3                                                                           CH                                Q-3                                                                               1  H  H    CH.sub.3                                                                              F   H      H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               1  H  H    CH.sub.3                                                                              Cl  H      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               1  H  H    CH.sub.3                                                                              Br  H      H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               1  H  H    CH.sub.2 CH.sub.3                                                                     Cl  Cl     H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               1  H  H    CH.sub.3                                                                              CH.sub.3                                                                           H      H    CH.sub.3                                                                           OCH.sub.3                                                                          CH                                Q-3                                                                               1  H  H    CH.sub.3                                                                              CN  H      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               1  H  H    CH.sub.3                                                                              CN  CN     H    CH.sub.3                                                                           OCH.sub.3                                                                          N                                 Q-3                                                                               1  H  H    CH.sub.3                                                                              CH.sub.3                                                                           Br     H    CH.sub.3                                                                           CH.sub.3                                                                           CH                                Q-3                                                                               1  H  H    CH.sub.3                                                                              F   Br     H    Cl  OCH.sub.3                                                                          CH                                Q-3                                                                               1  H  3-CH.sub.3                                                                          CH.sub.3                                                                              F   H      H    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                Q-3                                                                               1  H  5-OCH.sub.3                                                                         CH.sub.3                                                                              Cl  H      CH.sub.3                                                                            CH.sub.3                                                                           CH.sub.3                                                                           N                                 Q-3                                                                               1  H  5-Cl CH.sub.3                                                                              Cl  Cl     CH.sub.2 CH.sub.3                                                                   CH.sub.3                                                                           OCH.sub.3                                                                          N                                 __________________________________________________________________________     Q   n   R   R.sub.1                                                                              R.sub.7                                                                              R.sub.8 X    Y    Z    m.p. (°C.)               __________________________________________________________________________     Q-4 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH   197-199                         Q-4 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH   192-194                         Q-4 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH   194-196                         Q-4 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-4 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           N    155-158                         Q-4 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N    150-152                         Q-4 0   H   H     H     H       Cl   OCH.sub.3                                                                           CH   182-184                         Q-4 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-4 0   H   H     H     Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     Cl      Cl   OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-4 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-4 0   H   H     H     F       OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-4 0   H   H     H     F       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     F       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 0   H   H     H     F       Cl   OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 0   H   H     H     CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-4 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-4 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-4 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 0   H   H     H     CO.sub.2 CH.sub.3                                                                      Cl   OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     OH      CH.sub.3                                                                            CH.sub.3                                                                            CH   148-150                         Q-4 0   H   H     H     OH      CH.sub.3                                                                            OCH.sub.3                                                                           CH   163-164                         Q-4 0   H   H     H     OH      OCH.sub.3                                                                           OCH.sub.3                                                                           CH   133-136                         Q-4 0   H   H     H     OH      CH.sub.3                                                                            OCH.sub.3                                                                           N    165-167                         Q-4 0   H   H     H     OH      OCH.sub.3                                                                           OCH.sub.3                                                                           N    160-162                         Q-4 0   H   H     H     OH      Cl   OCH.sub.3                                                                           CH   138-140                         Q-4 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     SCH.sub.3                                                                              CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-4 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-4 0   H   H     H     SCH.sub.3                                                                              Cl   OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-4 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 0   H   H     F     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-4 0   H   H     F     F       OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-4 0   H   H     Cl    Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     Cl    Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-4 0   H   H     F     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-4 0   H   H     F     CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-4 0   H   H     CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 0   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-4 0   H   H     Br    Br      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 0   H   H     OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 0   H   5-CH.sub.3                                                                           F     H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 0   H   6-CH.sub.3                                                                           Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 0   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 0   H   3-CH.sub.3                                                                           Br    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 0   H   5-CH.sub.3                                                                           H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 0   H   5-OCH.sub.3                                                                          H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-4 0   H   6-SCH.sub.3                                                                          H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 0   H   5-Cl  Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 0   H   3-Cl  F     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-4 0   H   5-OCH.sub.2 F                                                                        Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 0   CH.sub.3                                                                           H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-4 1   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 1   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 1   H   H     F     Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-4 1   H   H     CH.sub.3                                                                             Cl      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-4 1   H   H     F     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 1   H   H     Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 1   H   H     Br    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 1   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 1   H   H     CH.sub.3                                                                             H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-4 1   H   H     CN    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 1   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-4 1   H   H     CH.sub.3                                                                             Br      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-4 1   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-4 1   H   5-CH.sub.3                                                                           F     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-4 1   H   5-OCH.sub. 3                                                                         Cl    H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-4 1   H   5-Cl  Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-5 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-5 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     H       Cl   OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-5 0   H   H     H     Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     Cl      Cl   OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-5 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-5 0   H   H     H     F       OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-5 0   H   H     H     F       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     F       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     F       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     F       Cl   OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-5 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-5 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-5 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     CO.sub.2 CH.sub.3                                                                      Cl   OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-5 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     SCH.sub.3                                                                              CH.sub.3                                                                            CH.sub.3                                                                            Cl                                   Q-5 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-5 0   H   H     H     SCH.sub.3                                                                              Cl   OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     SO.sub.3 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-5 0   H   H     H     SO.sub.3 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   H     H     SO.sub.3 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 0   H   H     F     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-5 0   H   H     F     F       OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-5 0   H   H     Cl    Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     Cl    Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-5 0   H   H     F     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-5 0   H   H     F     CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-5 0   H   H     CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 0   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-5 0   H   H     Br    Br      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     CO.sub.2 CH.sub.3                                                                    CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 0   H   H     OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   6-CH.sub.3                                                                           CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   3-CH.sub.3                                                                           CH.sub.3                                                                             H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-5 0   H   5-CH.sub.3                                                                           F     H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 0   H   5-CH.sub.3                                                                           Cl    H       OCH.sub. 3                                                                          OCH.sub.3                                                                           N                                    Q-5 0   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   6-CH.sub.3                                                                           Br    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 0   H   3-CH.sub.3                                                                           H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 0   H   5-OCH.sub.3                                                                          H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-5 0   H   5-SCH.sub.3                                                                          H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 0   H   5-Cl  Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 0   H   6-Cl  F     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-5 0   H   5-OCH.sub.2 F                                                                        Cl    F       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 0   CH.sub.3                                                                           H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-5 1   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 1   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 1   H   H     F     Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-5 1   H   H     CH.sub.3                                                                             Cl      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-5 1   H   H     F     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 1   H   H     Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 1   H   H     Br    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 1   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 1   H   H     CH.sub.3                                                                             H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-5 1   H   H     CN    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 1   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-5 1   H   H     CH.sub.3                                                                             Br      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-5 1   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-5 1   H   3-CH.sub.3                                                                           F     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-5 1   H   5-OCH.sub.3                                                                          Cl    H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-5 1   H   6-Cl  Cl    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-6 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-6 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     H       Cl   OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-6 0   H   H     H     Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     Cl      Cl   OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-6 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-6 0   H   H     H     F       OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-6 0   H   H     H     F       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     F       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     F       Cl   OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-6 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-6 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH   OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-6 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     CO.sub.2 CH.sub.3                                                                      Cl   OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-6 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     SCH.sub.3                                                                              CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-6 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-6 0   H   H     H     SCH.sub.3                                                                              Cl   OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-6 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 0   H   H     F     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-6 0   H   H     F     F       OCH.sub.3                                                                           CH.sub.3                                                                            Cl                                   Q-6 0   H   H     Cl    Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     Cl    Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-6 0   H   H     F     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-6 0   H   H     F     CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-6 0   H   H     CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-6 0   H   H     Br    Br      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   H   H     OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub. 3                                                                          CH                                   Q-6 0   H   5-CH.sub.3                                                                           CH.sub.3                                                                             H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-6 0   H   6-CH.sub.3                                                                           F     H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 0   H   3-CH.sub.3                                                                           Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 0   H   5-CH.sub.3                                                                           Br    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 0   H   6-CH.sub.3                                                                           H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   H   5-OCH.sub.3                                                                          H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-6 0   H   5-SCH.sub.3                                                                          H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 0   H   5-Cl  Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 0   H   3-Cl  F     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-6 0   H   5-OCH.sub.2 F                                                                        Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 0   CH.sub.3                                                                           H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-6 1   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 1   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 1   H   H     F     Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-6 1   H   H     CH.sub.3                                                                             Cl      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-6 1   H   H     F     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 1   H   H     Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 1   H   H     Br    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 1   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 1   H   H     CH.sub.3                                                                             H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-6 1   H   H     CN    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 1   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-6 1   H   H     CH.sub.3                                                                             Br      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-6 1   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-6 1   H   3-CH.sub.3                                                                           F     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-6 1   H   3-OCH.sub.3                                                                          Cl    H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-6 1   H   5-Cl  Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-7 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-7 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub. 3                                                                          N                                    Q-7 0   H   H     H     H       Cl   OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-7 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-7 0   H   H     H     Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     Cl      Cl   OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-7 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-7 0   H   H     H     F       OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-7 0   H   H     H     F       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     F       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 0   H   H     H     F       Cl   OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 0   H   H     H     CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub. 3                                                                          N                                    Q-7 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-7 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-7 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-7 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 0   H   H     H     CO.sub.2 CH.sub.3                                                                      Cl   OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-7 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     SCH.sub.3                                                                              CH.sub.3                                                                            CH.sub.3                                                                            Cl                                   Q-7 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-7 0   H   H     H     SCH.sub.3                                                                              Cl   OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-7 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 0   H   H     F     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-7 0   H   H     F     F       OCH.sub.3                                                                           CH.sub.3                                                                            Cl                                   Q-7 0   H   H     Cl    Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     Cl    Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-7 0   H   H     F     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-7 0   H   H     F     CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-7 0   H   H     CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 0   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-7 0   H   H     Br    Br      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 0   H   H     OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   3-CH.sub.3                                                                           CH.sub.3                                                                             H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   5-CH.sub.3                                                                           CH.sub.3                                                                             H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   CH.sub.3                                                                           H     CH.sub.3                                                                             H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-7 0   CH.sub.3                                                                           H     F     H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 0   H   5-CH.sub.3                                                                           Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 0   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   H     Br    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 0   H   5-CH.sub.3                                                                           H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 0   H   6-OCH.sub.3                                                                          H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-7 0   H   5-SCH.sub.3                                                                          H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 0   H   3-Cl  Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 0   H   5-Cl  F     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-7 0   H   3-OCH.sub.2 F                                                                        Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 0   CH.sub.3                                                                           H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-7 1   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 1   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 1   H   H     F     Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-7 1   H   H     CH.sub.3                                                                             Cl      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-7 1   H   H     F     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 1   H   H     Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 1   H   H     Br    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 1   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 1   H   H     CH.sub.3                                                                             H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-7 1   H   H     CN    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 1   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-7 1   H   H     CH.sub.3                                                                             Br      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-7 1   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-7 1   H   5-CH.sub.3                                                                           F     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-7 1   H   5-OCH.sub.3                                                                          Cl    H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-7 1   H   5-Cl  Cl    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-8 0   H   H     H     H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     H       Cl   OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-8 0   H   H     H     Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     Cl      Cl   OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-8 0   H   H     H     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     F       OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     F       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     F       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     F       Cl   OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-8 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     CO.sub.2 CH.sub.3                                                                      Cl   OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-8 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   H     H     SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     SCH.sub.3                                                                              CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     SCH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     SCH.sub.3                                                                              Cl   OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 0   H   H     F     F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 0   H   H     F     F       OCH.sub.3                                                                           CH.sub.3                                                                            Cl                                   Q-8 0   H   H     Cl    Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     Cl    Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-8 0   H   H     F     Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                    Q-8 0   H   H     F     CH.sub.3                                                                               CH.sub.3                                                                            CH.sub. 3                                                                           CH                                   Q-8 0   H   H     CH.sub.3                                                                             CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     CH.sub.3                                                                             CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-8 0   H   H     Br    Br      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   H     CN    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   H     OCH.sub.3                                                                            OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     Br      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 0   H   H     H     Br      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   H     H     Br      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   3-CH.sub.3                                                                           CH.sub.3                                                                             H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-8 0   H   5-CH.sub.3                                                                           F     H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 0   H   H     Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   H     Br    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 0   H   5-CH.sub.3                                                                           H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   H   5-OCH.sub.3                                                                          H     H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 0   H   5-SCH.sub.3                                                                          H     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 0   H   5-Cl  Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 0   H   6-Cl  F     F       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-8 0   H   5-OCH.sub.2 F                                                                        Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 0   CH.sub.3                                                                           H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                    Q-8 1   H   H     H     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 1   H   H     F     F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 1   H   H     F     Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-8 1   H   H     CH.sub.3                                                                             Cl      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                   Q-8 1   H   H     F     H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 1   H   H     Cl    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 1   H   H     Br    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 1   H   H     Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 1   H   H     CH.sub.3                                                                             H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                   Q-8 1   H   H     CN    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 1   H   H     CN    CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    Q-8 1   H   H     CH.sub.3                                                                             Br      CH.sub.3                                                                            CH.sub.3                                                                            CH                                   Q-8 1   H   H     F     Br      Cl   OCH.sub.3                                                                           CH                                   Q-8 1   H   5-CH.sub.3                                                                           F     H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                   Q-8 1   H   3-OCH.sub.3                                                                          Cl    H       CH.sub.3                                                                            CH.sub.3                                                                            N                                    Q-8 1   H   5-Cl  Cl    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                    __________________________________________________________________________     Q  n  R  R.sub.1                                                                              R.sub.3                                                                             R.sub.7                                                                             R.sub.8 X    Y    Z   m.p. (°C.)               __________________________________________________________________________     Q-9                                                                               0  H  H     CH.sub.3                                                                            H    H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    H       CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    H       Cl   OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub. 3                                                                           H    CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    Cl      Cl   OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    F       CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    F       OCH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    F       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    F       CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    F       Cl   OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      Cl   OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SCH.sub.3                                                                              CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SCH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SCH.sub.3                                                                              Cl   OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            F    F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            F    F       OCH.sub.3                                                                           CH.sub.3                                                                            Cl                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            Cl   Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            Cl   Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            F    Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            F    CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            CH.sub.3                                                                            CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            CH.sub.3                                                                            CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            F    Br      Cl   OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            Br   Br      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            CN   CN      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            CN   CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            CN   CN      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            OCH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    Br      CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    Br      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            H    Br      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.2 CH.sub.3                                                                   H    H       CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            F    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            Cl   H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            F    F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  H     CH.sub.3                                                                            Br   H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  H     CH.sub.3                                                                            Cl   Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-9                                                                               0  H  5-SCH.sub.3                                                                          CH.sub.3                                                                            H    H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  5-Cl  CH.sub.3                                                                            Cl   H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               0  H  5-Cl  CH.sub.3                                                                            F    F       CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-9                                                                               0  H  5-OCH.sub.2 F                                                                        CH.sub.3                                                                            Cl   H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               0  CH.sub.3                                                                          H     CH.sub.3                                                                            H    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-9                                                                               1  H  H     CH.sub.3                                                                            H    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               1  H  H     CH.sub.3                                                                            F    F       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               1  H  H     CH.sub.3                                                                            F    Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-9                                                                               1  H  H     CH.sub.3                                                                            CH.sub.3                                                                            Cl      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-9                                                                               1  H  H     CH.sub.3                                                                            F    H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               1  H  H     CH.sub.3                                                                            Cl   H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               1  H  H     H    Br   H       CH.sub.3                                                                            OCH.sub. 3                                                                          N                                   Q-9                                                                               1  H  H     H    Cl   Cl      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               1  H  H     H    CH.sub.3                                                                            H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-9                                                                               1  H  H     H    CN   H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               1  H  H     H    CN   CN      CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-9                                                                               1  H  H     H    CH.sub.3                                                                            Br      CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-9                                                                               1  H  H     H    F    Br      Cl   OCH.sub.3                                                                           CH                                  Q-9                                                                               1  H  3-CH.sub.3                                                                           H    F    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-9                                                                               1  H  6-OCH.sub.3                                                                          CH.sub.3                                                                            Cl   H       CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-9                                                                               1  H  5-Cl  CH.sub.2 CH.sub.3                                                                   Cl   Cl      CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    H       CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    H       CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    H       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    H       CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    H       CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    H       OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub. 3                                                                           H    H       Cl   OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CH.sub.3                                                                               CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    Cl      Cl   OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    F       CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    F       OCH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    F       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    F       CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    F       Cl   OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CN      CH.sub. 3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    OCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    CO.sub.2 CH.sub.3                                                                      Cl   OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SO.sub.2 N(CH.sub.3).sub. 2                                                            OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SO.sub.2 N(CH.sub.3).sub.2                                                             OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SO.sub.2 N(CH.sub.3).sub.2                                                             CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SCH.sub.3                                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SCH.sub.3                                                                              CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SCH.sub.3                                                                              OCH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SCH.sub.3                                                                              Cl   OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            H    SO.sub.2 CH.sub.3                                                                      CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            F    F       CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            F    F       OCH.sub.3                                                                           CH.sub.3                                                                            Cl                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            Cl   Cl      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            Cl   Cl      CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            F    Cl      OCH.sub.3                                                                           CH.sub.3                                                                            N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            F    CH.sub.3                                                                               CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            CH.sub.3                                                                            CH.sub.3                                                                               OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            CH.sub.3                                                                            CH.sub.2 CH.sub.3                                                                      OCH.sub.3                                                                           OCH.sub.3                                                                           H                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            F    Br      Cl   OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            Br   Br      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            CN   CN      CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            CN   CN      OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H  H     CH.sub.3                                                                            CN   CN      OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H  H     CH.sub.3                                                                            OCH.sub.3                                                                           OCH.sub.3                                                                              CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  __________________________________________________________________________     Q  n  R   R.sub.1                                                                              R.sub.7                                                                            R.sub.8                                                                            R.sub.3  X    Y    Z   m.p. (°C.)               __________________________________________________________________________     Q-10                                                                              0  H   H     H   Br  CH.sub.3 CH.sub.3                                                                            CH.sub.3                                                                            CH.sub.3                            Q-10                                                                              0  H   H     H   Br  CH.sub.3 CH.sub.3                                                                            OCH.sub.3                                                                           CH.sub.3                            Q-10                                                                              0  H   H     H   Br  CH.sub.3 OCH.sub.3                                                                           OCH.sub.3                                                                           CH.sub.3                            Q-10                                                                              0  H   H     H   H   CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.3                                                     OCH.sub.3                                                                           CH.sub.3                                                                            N                                   Q-10                                                                              0  H   5-CH.sub.3                                                                           F   H   CH.sub.3 CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              0  H   H     Cl  H   CH.sub.3 OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H   H     F   F   CH.sub.3 CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H   H     Br  H   CH.sub.3 OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H   H     Cl  Cl  CH.sub.3 CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              0  H   6-CH.sub.3                                                                           H   H   CH.sub.2 CH.sub.2 CH.sub.3                                                              OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  H   5-OCH.sub.3                                                                          H   H   CH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-10                                                                              0  H   3-SCH.sub.3                                                                          H   H   CH.sub.2 CH.sub.2 CH.sub.3                                                              CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H   6-Cl  Cl  H   CH.sub.2 CH.sub.3                                                                       OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              0  H   5-Cl  F   F   CH.sub.3 CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-10                                                                              0  H   5-OCH.sub.2 F                                                                        Cl  H   CH.sub.3 OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              0  CH.sub.3                                                                           H     H   H   H        OCH.sub.3                                                                           OCH.sub.3                                                                           N                                   Q-10                                                                              1  H   H     H   H   H        OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              1  H   H     F   F   H        CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              1  H   H     F   Cl  CH.sub.3 CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-10                                                                              1  H   H     CH.sub.3                                                                           Cl  H        OCH.sub.3                                                                           CH.sub.3                                                                            CH                                  Q-10                                                                              1  H   H     F   H   H        CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              1  H   H     Cl  H   CH.sub.3 OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              1  H   H     Br  H   H        CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              1  H   H     Cl  Cl  CH.sub.3 CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              1  H   H     CH.sub.3                                                                           H   CH.sub.3 CH.sub.3                                                                            OCH.sub.3                                                                           CH                                  Q-10                                                                              1  H   H     CN  H   CH.sub.3 OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              1  H   H     CN  CN  H        CH.sub.3                                                                            OCH.sub.3                                                                           N                                   Q-10                                                                              1  H   H     CH.sub.3                                                                           Br  H        CH.sub.3                                                                            CH.sub.3                                                                            CH                                  Q-10                                                                              1  H   H     F   Br  CH.sub.3 Cl   OCH.sub.3                                                                           CH                                  Q-10                                                                              1  H   3-CH.sub.3                                                                           F   H   H        OCH.sub.3                                                                           OCH.sub.3                                                                           CH                                  Q-10                                                                              1  H   5-OCH.sub.3                                                                          Cl  H   CH.sub.3 CH.sub.3                                                                            CH.sub.3                                                                            N                                   Q-10                                                                              1  H   6-Cl  Cl  Cl  CH.sub.2 CH.sub.3                                                                       CH.sub.3                                                                            OCH.sub.3                                                                           N                                   __________________________________________________________________________     Q  n R R.sub.1                                                                          R.sub.3                                                                           R.sub.7                                                                           R.sub.8                                                                           R.sub.9                                                                           R.sub.10                                                                          R.sub.11                                                                          X        Y        Z  m.p. (°C.)              __________________________________________________________________________     Q-1                                                                               0 H H -- H  H  H  H  -- NHCH.sub.3                                                                              OCH.sub.2 CH.sub.3                                                                      N  203-206                        Q-1                                                                               0 H H -- H  H  H  H  -- CH.sub.3 SCH.sub.3                                                                               CH                                Q-1                                                                               0 H H -- H  H  Cl H  -- N(CH.sub.3)H                                                                            OCH.sub.2 CH.sub.3                                                                      N  154-158                        Q-1                                                                               0 H H -- Cl Cl H  H  -- OCH.sub.3                                                                               CH(OCH.sub.3).sub.2                                                                     CH                                Q-1                                                                               0 H H -- CH.sub.3                                                                          H  H  H  -- OCH.sub.3                                                                               OCH.sub.2 CH═CH.sub.2                                                               CH                                Q-1                                                                               0 H H -- CH.sub.3                                                                          H  H  Cl -- OCH.sub.3                                                                               OCH.sub.2 CH.sub.3                                                                      CH                                Q-1                                                                               0 H H -- F  F  H  H  -- OCH.sub.2 CH.sub.3                                                                      OCH.sub.2 F                                                                             N                                 Q-1                                                                               0 H H -- H  CN H  H  -- OCH.sub.3                                                                               SCH.sub.3                                                                               CH                                Q-1                                                                               0 H Cl                                                                               -- Br H  H  CH.sub.3                                                                          -- OCH.sub.3                                                                               Br       CH                                Q-1                                                                               0 H H -- H  Br H  H  -- OCH.sub.3                                                                               NH.sub.2 CH                                Q-1                                                                               0 H H -- H  Br Cl H  -- OCH.sub.3                                                                               NHCH.sub.3                                                                              N                                 Q-1                                                                               0 H H -- F  F  Cl F  -- CH.sub.3 OCH.sub.2 C.tbd.CH                                                                      CH                                Q-1                                                                               0 H H -- F  CN H  H  -- OCH.sub.3                                                                               CH.sub.2 CF.sub.3                                                                       CH                                Q-1                                                                               0 H H -- H  H  H  H  -- OCF.sub.2 CH.sub.3                                                                      CH.sub.3 N                                 Q-1                                                                               0 H H -- H  H  H  H  -- OCH.sub.3                                                                               C.tbd.CH CH                                Q-1                                                                               0 H H -- Cl Cl H  H  -- OCH.sub.3                                                                                ##STR51##                                                                              CH                                Q-2                                                                               0 H H -- H  H  H  H  H  OCH.sub.3                                                                               OCH.sub.2 CH.sub.3                                                                      N                                 Q-2                                                                               0 H H -- Cl H  H  H  H  CH.sub.3 OCH.sub.3                                                                      CH.sub.2 CF.sub.3                                                                       N                                 Q-2                                                                               0 H H -- Cl H  CH.sub.3                                                                          H  H  OCH.sub.3                                                                               N(CH.sub.3).sub.2                                                                       N                                 Q-4                                                                               0 H H -- H  H  H  H  -- CH.sub.3 CH.sub.2 CH.sub.3                                                                       CH                                Q-4                                                                               0 H H -- H  H  H  H  -- OCH.sub.3                                                                               OCH.sub.2 OCH.sub.3                                                                     CH                                Q-5                                                                               0 H H -- Cl H  H  H  -- OCH.sub.3                                                                               SCH.sub.2 CH.sub.3                                                                      CH                                Q-5                                                                               0 H H -- Cl Cl H  H  -- OCF.sub.2 H                                                                             CH.sub.2 CH.sub.3                                                                       CH                                Q-5                                                                               0 H H -- CH.sub.3                                                                          H  H  CH.sub.3                                                                          -- OCH.sub.3                                                                               F        CH                                Q-9                                                                               0 H H CH.sub.3                                                                          H  H  H  H  -- SCH.sub.2 CH.sub.2 F                                                                    HNCH.sub.3                                                                              CH                                Q-9                                                                               0 H H H  H  H  H  F  -- OCH.sub.3                                                                               OCH.sub.2 CH═CH.sub.2                                                               CH                                Q-3                                                                               0 H H CH.sub.3                                                                          H  H  H  H  H  OCH.sub.2 CH.sub.3                                                                      SCH.sub.2 CH.sub.3                                                                      N                                 Q-3                                                                               0 H H CH.sub.3                                                                          F  H  H  Br CH.sub.3                                                                          OCH.sub.3                                                                               I        CH                                Q-3                                                                               0 H H H  H  H  H  H  H  OCH.sub.2 OCH.sub.2 CH.sub.3                                                            CH.sub.3 CH                                Q-7                                                                               0 H H -- H  H  H  H  -- OCH.sub. 2 OCH.sub.2 CH.sub.3                                                           OCH.sub.3                                                                               N                                 Q-7                                                                               0 H H -- H  H  H  H  -- OCHF.sub.2                                                                              N(CH.sub.3).sub.2                                                                       CH                                Q-7                                                                               0 H H -- Cl H  H  H  -- OCH.sub.3                                                                               N(OCH.sub.3)CH.sub.3                                                                    N                                 __________________________________________________________________________     General Structure I (wherein R.sub.12 and R.sub.13 are H)                      (W = S)                                                                        Q  n  R R.sub.1                                                                             R.sub.7                                                                              R.sub.8                                                                               R.sub.9                                                                           R.sub.10                                                                          R.sub.11                                                                           X   Y   Z  m.p. (°C.)               __________________________________________________________________________     Q-1                                                                               0  H H    H     H      H  H  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    H     H      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H     H      H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H 5-CH.sub.3                                                                          H     H      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H     H      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H     H      H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H     H      H  H  --  Cl  OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H     F      H  H  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    H     F      H  H  --  CH.sub.3                                                                           CH.sub.3                                                                           N                                  Q-1                                                                               0  H H    H     F      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H     Cl     H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H     Cl     H  H  --  CH.sub.3                                                                           CH.sub.3                                                                           N                                  Q-1                                                                               0  H H    Cl    H      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    Cl    H      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H     Br     H  H  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    Br    H      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    Br    H      H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H     I      H  H  --  CH.sub.3                                                                           CH.sub.3                                                                           N                                  Q-1                                                                               0  H H    I     H      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H     CN     H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    CN    H      H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H     CH.sub.3                                                                              H  H  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    H     CH.sub.3                                                                              H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H     CH.sub.3                                                                              H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    CH.sub.3                                                                             H      H  H  --  Cl  OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    CH.sub.3                                                                             H      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H     CH.sub.2 CH.sub.3                                                                     H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    CH.sub.2 CH.sub.3                                                                    H      H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H     CH.sub.2 CH.sub.3                                                                     H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                 Q-1                                                                               0  H H    H     CH.sub.2 CH.sub.3 CH.sub.3                                                            H  H  --  CH.sub.3                                                                           OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H     Cl     H  H  --  CH.sub.3                                                                           CH.sub.3                                                                           CH                                 Q-1                                                                               0  H H    H     Cl     H  H  --  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                  Q-1                                                                               0  H H    H     Cl     H  H  --  Cl  OCH.sub.3                                                                          CH                                 __________________________________________________________________________

                                      TABLE IA                                     __________________________________________________________________________     General Structure I (wherein R.sub.12 is OH; R.sub.13 is H)                    Q  n R R.sub.1                                                                          R.sub.7                                                                           R.sub.8                                                                               R.sub.9                                                                           R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  m.p. (°C.)                       __________________________________________________________________________     Q-1                                                                               1 H H H  H      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH 148-150                                 Q-1                                                                               1 H H H  H      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH 140-142                                 Q-1                                                                               1 H H H  H      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH 148-150                                 Q-1                                                                               1 H H H  H      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H  H      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N  109-111                                 Q-1                                                                               1 H H H  H      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N  147-149                                 Q-1                                                                               1 H H H  H      H  H  -- Cl  OCH.sub.3                                                                          CH 124-126                                 Q-1                                                                               1 H H H  F      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H  F      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H  F      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  Cl     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  Cl     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H Cl H      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl H      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  Br     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H Br H      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br H      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  I      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H I  H      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  CN     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H CN H      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  CH.sub.3                                                                              H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H  CH.sub.3                                                                              H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  CH.sub.3                                                                              H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CH.sub.3                                                                          H      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H CH.sub.3                                                                          H      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  CH.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  CH.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  CH.sub.2 CH.sub.2 CH.sub.3                                                            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  OCH.sub.3                                                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H  OCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H CH.sub.3 O                                                                        H      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  OCH.sub.2 CH.sub.3                                                                    H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H  CO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  CO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  CO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  CO.sub.2 CH.sub.3                                                                     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  CO.sub.2 CH.sub.2 CH.sub.3                                                            H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  SO.sub.2 N(CH.sub.3).sub.2                                                            H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H  SCH.sub.3                                                                             H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  SCH.sub.3                                                                             H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  H  -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  SO.sub.2 CH.sub.2 CH.sub.3                                                            H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  CH.sub.3                                                                              H  CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  CH.sub.3                                                                              H  CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  CH.sub.3                                                                              CH.sub.3                                                                          H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H  CH.sub.3                                                                              H  F  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  CH.sub.3                                                                              H  F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  CH.sub.3                                                                              H  F  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  CH.sub.3                                                                              H  Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  CH.sub.3                                                                              Br H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  F      H  CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  F      H  CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  Cl     H  CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  Cl     H  F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  Cl     H  Cl -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  Cl     H  Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  Cl     H  Br -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                          -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  Cl -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-I                                                                               1 H H H  SO.sub.2 CH.sub.3                                                                     H  Br -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H F  F      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H F  F      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H F  F      H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H F  F      H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H F  F      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H F  F      H  H  -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl Cl     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl Cl     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl Cl     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl Cl     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl Cl     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H Cl Cl     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H Cl Cl     H  H  -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br Br     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br Br     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br Br     H  H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br Br     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br Br     H  H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H I  I      H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN CN     H  H  -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN CN     H  H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H CN CN     H  H  -- CH.sub.3                                                                           OCH.sub. 3                                                                         CH                                         Q-1                                                                               1 H H F  F      H  CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H F  F      H  CH.sub.3                                                                          -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H F  F      H  F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H F  F      H  Cl -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H F  F      H  Br -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl Cl     H  CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl Cl     H  CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl Cl     H  Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Cl Cl     H  F  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Cl Cl     H  Br -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br Br     H  CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H Br Br     H  CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br Br     H  Cl -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H Br Br     H  Cl -- CH.sub.3                                                                           CH.sub.3                                                                           N                                          Q-1                                                                               1 H H Br Br     Cl H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br Br     H  F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H Br Br     H  Br -- Cl  OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN CN     H  CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN CN     H  CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CN CN     H  F  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H CH.sub.3                                                                          CH.sub.3                                                                              H  CH.sub.3                                                                          -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                          Q-1                                                                               1 H H CH.sub.3                                                                          CH.sub.3                                                                              H  CH.sub.3                                                                          -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                         Q-1                                                                               1 H H CH.sub.3                                                                          CH.sub.3                                                                              H  CH.sub.3                                                                          -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                         Q-1                                                                               1 H H CH.sub.3                                                                          CH.sub.3                                                                              CH.sub.3                                                                          H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                         __________________________________________________________________________

                                      TABLE IB                                     __________________________________________________________________________     General Structure I (wherein R.sub.12 is OH; R.sub.13 is CH.sub.3)             Q  n R R.sub.1                                                                          R.sub.7                                                                          R.sub.8                                                                           R.sub.9                                                                          R.sub.10                                                                         R.sub.11                                                                          X   Y   Z  m.p. (°C.)                              __________________________________________________________________________     Q-1                                                                               1 H H H H  H H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                                Q-1                                                                               1 H H H H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                                Q-1                                                                               1 H H H H  H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                                Q-1                                                                               1 H H H H  H H -- CH.sub.3                                                                           CH.sub.3                                                                           N                                                 Q-1                                                                               1 H H H H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                                 Q-1                                                                               1 H H H H  H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                                 Q-1                                                                               1 H H H H  H H -- Cl  OCH.sub.3                                                                          CH                                                Q-1                                                                               1 H H H F  H H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                                Q-1                                                                               1 H H H F  H H -- CH.sub.3                                                                           CH.sub. 3                                                                          N                                                 Q-1                                                                               1 H H H F  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                                Q-1                                                                               1 H H H Cl H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                                Q-1                                                                               1 H H H Cl H H -- CH.sub.3                                                                           CH.sub.3                                                                           N                                                 Q-1                                                                               1 H H Cl                                                                               H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                                Q-1                                                                               1 H H Cl                                                                               H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                                 Q-1                                                                               1 H H H Br H H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                                Q-1                                                                               1 H H Br                                                                               H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                                Q-1                                                                               1 H H Br                                                                               H  H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                                Q-1                                                                               1 H H H I  H H -- CH.sub.3                                                                           CH.sub.3                                                                           N                                                 Q-1                                                                               1 H H I H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                                 Q-1                                                                               1 H H H CN H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                                 Q-1                                                                               1 H H CN                                                                               H  H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                                Q-1                                                                               1 H H H CH.sub.3                                                                          H H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                                __________________________________________________________________________

                                      TABLE IC                                     __________________________________________________________________________     General Structure I (wherein R.sub.12 is OCH.sub.3 ; R.sub.13 is H)            Q  n R R.sub.1                                                                          R.sub.7                                                                           R.sub.8                                                                           R.sub.9                                                                          R.sub.10                                                                         R.sub.11                                                                          X   Y   Z  m.p. (°C.)                             __________________________________________________________________________     Q-1                                                                               1 H H H  H  H H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                               Q-1                                                                               1 H H H  H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                               Q-1                                                                               1 H H H  H  H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                               Q-1                                                                               1 H H H  H  H H -- CH.sub.3                                                                           CH.sub.3                                                                           N                                                Q-1                                                                               1 H H H  H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                                Q-1                                                                               1 H H H  H  H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                                Q-1                                                                               1 H H H  H  H H -- Cl  OCH.sub.3                                                                          CH                                               Q-1                                                                               1 H H H  F  H H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                               Q-1                                                                               1 H H H  F  H H -- CH.sub.3                                                                           CH.sub. 3                                                                          N                                                Q-1                                                                               1 H H H  F  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                               Q-1                                                                               1 H H H  Cl H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                               Q-1                                                                               1 H H H  Cl H H -- CH.sub.3                                                                           CH.sub.3                                                                           N                                                Q-1                                                                               1 H H Cl H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                               Q-1                                                                               1 H H Cl H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                                Q-1                                                                               1 H H H  Br H H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                               Q-1                                                                               1 H H Br H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                               Q-1                                                                               1 H H Br H  H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                               Q-1                                                                               1 H H H  I  H H -- CH.sub.3                                                                           CH.sub.3                                                                           N                                                Q-1                                                                               1 H H I  H  H H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                                Q-1                                                                               1 H H H  CN H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                                Q-1                                                                               1 H H CN H  H H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                               Q-1                                                                               1 H H H  CH.sub.3                                                                          H H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                               __________________________________________________________________________

                  TABLE ID                                                         ______________________________________                                         General Structure I (wherein R.sub.12 is OH; R.sub.13 is CH.sub.3)                                                              m.p.                          Q    n     R     R.sub.1                                                                            R.sub.7                                                                            R.sub.8                                                                               X     Y     Z    (°C.)                  ______________________________________                                         Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            CH.sub.3                                                                             N                                  Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   F      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CN     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CN     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     Cl    OCH.sub.3                                                                            CH                                 ______________________________________                                    

                  TABLE IE                                                         ______________________________________                                         General Structure I (wherein R.sub.12 is OH; R.sub.13 is CH.sub.3)                                                              m.p.                          Q    n     R     R.sub.1                                                                            R.sub.7                                                                            R.sub.8                                                                               X     Y     Z    (°C.)                  ______________________________________                                         Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            CH.sub.3                                                                             N                                  Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   F      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CN     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CN     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     Cl    OCH.sub.3                                                                            CH                                 ______________________________________                                    

                  TABLE IF                                                         ______________________________________                                         General Structure I (wherein R.sub.12 is OCH.sub.3 ; R.sub.13 is H)                                                             m.p.                          Q    n     R     R.sub.1                                                                            R.sub.7                                                                            R.sub.8                                                                               X     Y     Z    (°C.)                  ______________________________________                                         Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            CH.sub.3                                                                             N                                  Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   F      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CN     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CN     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     Cl    OCH.sub.3                                                                            CH                                 ______________________________________                                    

                  TABLE IG                                                         ______________________________________                                         General Structure I (wherein R.sub.12 is OCH.sub.3 ; R.sub.13 is               CH.sub.3)                                                                                                                       m.p.                          Q    n     R     R.sub.1                                                                            R.sub.7                                                                            R.sub.8                                                                               X     Y     Z    (°C.)                  ______________________________________                                         Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   H      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   H      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   H      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CH.sub.3                                                                              OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CH.sub.3                                                                              CH.sub.3                                                                             OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     CH.sub.3                                                                             OCH.sub. 3                                                                           CH                                 Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            CH.sub.3                                                                             N                                  Q-4  1     H     H   H   Cl     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   Cl     Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   F      CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   F      OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   F      CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   F      Cl    OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CN     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CN     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   OCH.sub.3                                                                             OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                             CH.sub.3                                                                             CH                                 Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            N                                  Q-4  1     H     H   H   CO.sub.2 CH.sub.3                                                                     Cl    OCH.sub.3                                                                            CH                                 ______________________________________                                    

                                      TABLE II                                     __________________________________________________________________________     General Structure II (wherein R.sub.12 and R.sub.13 are H)                                                                                m.p.                L   Q.sub.1                                                                           n  R   R.sub.1                                                                            R.sub.2                                                                           R.sub.3                                                                               R.sub.2 /R.sub.3                                                                   R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  (°C.)        __________________________________________________________________________     L-2 Q-1                                                                               0  H   H   --            H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-1                                                                               0  H   H   --            H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-1                                                                               0  H   H   --            Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-1                                                                               0  H   H   --            F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-1                                                                               0  H   H   --            H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-1                                                                               0  H   H   --            CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-1                                                                               0  H   H   --            H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-1                                                                               0  H   H   --            H  F    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-1                                                                               0  H   H   --            Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-1                                                                               0  H   H   --            Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-1                                                                               0  H   H   --            F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-1                                                                               0  H   H   --            H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-1                                                                               0  H   H   --            H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-1                                                                               0  H   CH.sub.3                                                                           --            H  H    H H  -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-1                                                                               0  CH.sub.3                                                                           H   --            H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-1                                                                               1  H   H   --            F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-1                                                                               1  H   H   --            H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               0  H   H   --            H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-2                                                                               0  H   H   --            H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2 Q-2                                                                               0  H   H   --            H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               0  H   H   --            Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-2                                                                               0  H   H   --            F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               0  H   H   --            H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               0  H   H   --            F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-2                                                                               0  H   H   --            Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               0  H   H   --            H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               0  H   H   --            CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               0  H   H   --            H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-2                                                                               0  H   H   --            H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               0  H   OCH.sub.3                                                                          --            H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2 Q-2                                                                               0  CH.sub.3                                                                           Cl  --            F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               1  H   H      --         H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-2                                                                               1  H   H      --         Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-2                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               0  H   H      CH.sub.3   H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-3                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               0  H   H      CH.sub.3   Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               0  H   H      CH.sub.3   F  F    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-3                                                                               0  H   H      CH.sub.3   H  Br   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-3                                                                               0  H   H      CH.sub.3   CH.sub.3                                                                          H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-3                                                                               0  H   H      CH.sub.3   H  OCH.sub.3                                                                           --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               0  H   H      CH.sub.3   H  F    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               0  H   H      CH.sub.3   Cl Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               0  H   H      CH.sub.3   Cl CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-3                                                                               0  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-3                                                                               0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               0  H   CH.sub.3                                                                              CH.sub.3   H  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               0  CH.sub.3                                                                           H      CH.sub.3   H  H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-3                                                                               1  H   H      CH.sub.3   F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-3                                                                               1  H   H      CH.sub.3   H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-4                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-4                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-4                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2 Q-4                                                                               0  CH.sub.3                                                                           Cl  --            F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               1  H   H   --            H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-4                                                                               1  H   H   --            Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-4                                                                               1  H   H   --            F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-5                                                                               0  H   H   --            H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-5                                                                               0  H   H   --            H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.                                                                           CH                     L-2 Q-5                                                                               0  H   H   --            Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-5                                                                               0  H   H   --            F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-5                                                                               0  H   H   --            H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-5                                                                               0  H   H   --            CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-5                                                                               0  H   H   --            H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-5                                                                               0  H   H   --            H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-5                                                                               0  H   H   --            Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-5                                                                               0  H   H   --            Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-5                                                                               0  H   H   --            F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-5                                                                               0  H   H   --            H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-5                                                                               0  H   H   --            H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-5                                                                               0  H   CH.sub.3                                                                           --            H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-5                                                                               0  CH.sub.3                                                                           H   --            H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-5                                                                               1  H   H   --            F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-5                                                                               1  H   H   --            H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               0  H   H   --            H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-6                                                                               0  H   H   --            H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2 Q-6                                                                               0  H   H   --            H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               0  H   H   --            Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-6                                                                               0  H   H   --            F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               0  H   H   --            H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               0  H   H   --            F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-6                                                                               0  H   H   --            Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               0  H   H   --            H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               0  H   H   --            CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               0  H   H   --            H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-6                                                                               0  H   H   --            H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               0  H   OCH.sub.3                                                                          --            H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2 Q-6                                                                               0  CH.sub.3                                                                           Cl  --            F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               1  H   H   --            H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-6                                                                               1  H   H   --            Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-6                                                                               1  H   H   --            F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               0  H   H   --            H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-7                                                                               0  H   H   --            H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               0  H   H   --            Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               0  H   H   --            F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-7                                                                               0  H   H   --            H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-7                                                                               0  H   H   --            CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-7                                                                               0  H   H   --            H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               0  H   H   --            H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               0  H   H   --            Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               0  H   H   --            Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-7                                                                               0  H   H   --            F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               0  H   H   --            H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-7                                                                               0  H   H   --            H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               0  H   CH.sub.3                                                                           --            H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               0  CH.sub.3                                                                           H   --            H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-7                                                                               1  H   H   --            F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-7                                                                               1  H   H   --            H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               0  H   H   --            H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-8                                                                               0  H   H   --            H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2 Q-8                                                                               0  H   H   --            H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               0  H   H   --            Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-8                                                                               0  H   H   --            F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               0  H   H   --            H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               0  H   H   --            F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-8                                                                               0  H   H   --            Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               0  H   H   --            H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               0  H   H   --            CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-8                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2 Q-8                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-8                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-8                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               0  H   H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-9                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               0  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               0  H   H      CH.sub.3   F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-9                                                                               0  H   H      CH.sub.3   H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-9                                                                               0  H   H      CH.sub.3   CH.sub. 3                                                                         H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-9                                                                               0  H   H      CH.sub.3   H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               0  H   H      CH.sub.3   H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               0  H   H      CH.sub.3   Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               0  H   H      CH.sub.3   Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-9                                                                               0  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-2 Q-9                                                                               0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               0  H   CH.sub.3                                                                              CH.sub.3   H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               0  CH.sub.3                                                                           H      CH.sub. 3  H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-9                                                                               1  H   H      CH.sub.3   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-9                                                                               1  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-2 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              0  H   H      CH.sub.3   Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-2 Q-10                                                                              0  H   H      CH.sub.3   F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              0  H   H      CH.sub.3   H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              0  H   H      CH.sub.3   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-10                                                                              0  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              0  H   H             CH.sub.3                                                                           H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              0  H   H             CH.sub.3                                                                           CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              0  H   H             CH.sub.3                                                                           H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-2 Q-10                                                                              0  H   H             CH.sub.3                                                                           H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              0  H   OCH.sub.3     CH.sub.3                                                                           H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-2 Q-10                                                                              0  CH.sub.3                                                                           Cl            CH.sub.3                                                                           F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              1  H   H             CH.sub.3                                                                           H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-2 Q-10                                                                              1  H   H             CH.sub.3                                                                           Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-2 Q-10                                                                              1  H   H             CH.sub.3                                                                           F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           H  F    H H  -- CH.sub.3                                                                           OCH.sub.                                                                           CH                     L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-1                                                                               0  H   H             CH.sub.3                                                                           H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-1                                                                               0  H   CH.sub.3      CH.sub.3                                                                           H  H    H H  -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-1                                                                               0  CH.sub.3                                                                           H             CH.sub.3                                                                           H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-1                                                                               1  H   H             CH.sub.3                                                                           F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-1                                                                               1  H   H             CH.sub.3                                                                           H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               0  H   H             CH.sub.3                                                                           H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-2                                                                               0  H   H             CH.sub.3                                                                           H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3 Q-2                                                                               0  H   H             CH.sub.3                                                                           H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               0  H   H             CH.sub.3                                                                           Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-2                                                                               0  H   H             CH.sub.3                                                                           F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               0  H   H             CH.sub.3                                                                           H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               0  H   H   CH.sub.3                                                                          --         F  F      -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-2                                                                               0  H   H   CH.sub.3                                                                          --         Cl Cl     -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               0  H   H   CH.sub.3                                                                          --         H  CH.sub.3                                                                              -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               0  H   H   CH.sub.3                                                                          --         CH.sub.3                                                                          CH.sub.3                                                                              -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               0  H   H   CH.sub.3                                                                          --         H  CO.sub.2 CH.sub.3                                                                     -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-2                                                                               0  H   H   CH.sub.3                                                                          --         H  F      -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               0  H   OCH.sub.3                                                                          CH.sub.3                                                                          --         H  Cl     -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3 Q-2                                                                               0  CH.sub.3                                                                           Cl  CH.sub.3                                                                          --         F  CH.sub.3                                                                              -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               1  H   H   CH.sub.3                                                                          --         H  Cl     -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-2                                                                               1  H   H   CH.sub.3                                                                          --         Cl Cl     -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-2                                                                               1  H   H   CH.sub.3                                                                          --         F  CH.sub.3                                                                              -- H  Cl  OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  H      -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  Cl     -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   Cl Cl     -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   F  F      -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  Br     -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   CH.sub.3                                                                          H      -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  OCH.sub.3                                                                             -- H  Cl  OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  F      -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   Cl Br     -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   Cl CH.sub.3                                                                              -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   F  CH.sub.3                                                                              -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                         H  Cl     -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-3                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  CH.sub.3                                                                              -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               0  H   CH.sub.3                                                                           CH.sub.3                                                                          CH.sub.3   H  H      -- H  Cl  OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               0  CH.sub.3                                                                           H   CH.sub.3                                                                          CH.sub.3   H  H      -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-3                                                                               1  H   H   CH.sub.3                                                                          CH.sub.3   F  F      -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-3                                                                               1  H   H   CH.sub.3                                                                          CH.sub.3   H  H      -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3                                                                          --         H  H      -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3                                                                          --         H  H      -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3                                                                          --         H  H      -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3                                                                          --         Cl H      -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-4                                                                               0  H   H   CH.sub.3      F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3      H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3      F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-4                                                                               0  H   H   CH.sub.3      Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3      H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3      CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3      H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-4                                                                               0  H   H   CH.sub.3      H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               0  H   OCH.sub.3                                                                          CH.sub.3      H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3 Q-4                                                                               0  CH.sub.3                                                                           Cl  CH.sub.3      F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               1  H   H   CH.sub.3      H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-4                                                                               1  H   H   CH.sub.3      Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-4                                                                               1  H   H   CH.sub.3      F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               0  H   H   CH.sub.3      H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-5                                                                               0  H   H   CH.sub.3      H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               0  H   H   CH.sub.3      Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               0  H   H   CH.sub.3      F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-5                                                                               0  H   H   CH.sub.3      H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-5                                                                               0  H   H   CH.sub.3      CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-5                                                                               0  H   H   CH.sub.3      H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               0  H   H   CH.sub.3      H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               0  H   H   CH.sub.3      Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               0  H   H   CH.sub.3      Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-5                                                                               0  H   H   CH.sub.3      F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               0  H   H   CH.sub.3      H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-5                                                                               0  H   H   CH.sub.3      H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               0  H   CH.sub.3                                                                           CH.sub.3      H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               0  CH.sub.3                                                                           H   CH.sub.3      H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-5                                                                               1  H   H   CH.sub.3      F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-5                                                                               1  H   H   CH.sub.3      H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-6                                                                               0  H   H   CH.sub.3      F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-6                                                                               0  H   H   CH.sub.3      Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-6                                                                               0  H   H   CH.sub.3      H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               0  H   OCH.sub.3                                                                          CH.sub.3      H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3 Q-6                                                                               0  CH.sub.3                                                                           Cl  CH.sub.3      F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               1  H   H   CH.sub.3      H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-6                                                                               1  H   H   CH.sub.3      Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-6                                                                               1  H   H   CH.sub.3      F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               0  H   H   CH.sub.3      H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-7                                                                               0  H   H   CH.sub.3      H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               0  H   H   CH.sub.3      Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               0  H   H   CH.sub.3      F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-7                                                                               0  H   H   CH.sub.3      H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-7                                                                               0  H   H   CH.sub.3      CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-7                                                                               0  H   H   CH.sub. 3     H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               0  H   H   CH.sub.3      H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               0  H   H   CH.sub.3      Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               0  H   H   CH.sub.3      Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-7                                                                               0  H   H   CH.sub.3      F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               0  H   H   CH.sub.3      H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-7                                                                               0  H   H   CH.sub.3      H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               0  H   CH.sub.3                                                                           CH.sub.3      H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               0  CH.sub.3                                                                           H   CH.sub.3      H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-7                                                                               1  H   H   CH.sub.3      F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-7                                                                               1  H   H   CH.sub.3      H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         H  H    --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         H  H    --   -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         H  H    --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         Cl H    --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         F  H    --   -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         H  Br   --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         F  F    --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         Cl Cl   --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         H  CH.sub.3                                                                            --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         CH.sub.3                                                                          CH.sub.3                                                                            --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         CH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                   --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-8                                                                               0  H   H   CH.sub.3                                                                          --         H  F    --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               0  H   OCH.sub.3                                                                          CH.sub.3                                                                          --         H  Cl   --   -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3 Q-8                                                                               0  CH.sub.3                                                                           Cl  CH.sub.3                                                                          --         F  CH.sub.3                                                                            --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               1  H   H   CH.sub.3                                                                          --         H  Cl   --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-8                                                                               1  H   H   CH.sub.3                                                                          --         Cl Cl   --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-8                                                                               1  H   H   CH.sub.3                                                                          --         F  CH.sub.3                                                                            --   -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  H    --   -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  Cl   --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   Cl Cl   --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   F  F    --   -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  Br   --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   CH.sub.3                                                                          H    --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  OCH.sub.3                                                                           --   -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  F    --   -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   Cl Br   --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   Cl CH.sub.3                                                                            --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   F  CH.sub.3                                                                            --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.3   H  Cl   --   -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-3 Q-9                                                                               0  H   H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                         H  CH.sub.3                                                                            --   -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               0  H   CH.sub.3                                                                           CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                         H  H    --   -- Cl  OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               0  CH.sub.3                                                                           H   CH.sub.3                                                                          CH.sub.2 CH.sub.2 CH.sub.3                                                                H  H    --   -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-9                                                                               1  H   H   CH.sub.3                                                                          CH.sub.3   F  F    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-9                                                                               1  H   H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                         H  H    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   H  H    --                                                                               --    CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   H  H    --                                                                               --    OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   H  H    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   Cl H    --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   F  H    --                                                                               --    Cl  OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   H  Br   --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   F  F    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   Cl Cl   --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   H  CH.sub.3                                                                            --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   H  CO.sub.2 CH.sub.3                                                                   --                                                                               --    CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-3 Q-10                                                                              0  H   H   CH.sub.3                                                                          CH.sub.3   H  F    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              0  H   OCH.sub.3                                                                          CH.sub.3                                                                          CH.sub.3   H  Cl   --                                                                               --    OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-3 Q-10                                                                              0  CH.sub.3                                                                           Cl  CH.sub.3                                                                          CH.sub.3   F  CH.sub.3                                                                            --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              1  H   H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                         H  Cl   --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-3 Q-10                                                                              1  H   H   CH.sub.3                                                                          CH.sub.3   Cl Cl   --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-3 Q-10                                                                              1  H   H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                         F  CH.sub.3                                                                            --                                                                               --    Cl  OCH.sub.3                                                                          CH                     L-4 Q-1                                                                               0  H   H   -- --         H  H    H H     CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-1                                                                               0  H   H   -- --         Cl Cl   H H     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-1                                                                               0  H   H   -- --         F  F    H H     CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-1                                                                               0  H   H   -- --         H  Br   H H     CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-1                                                                               0  H   H   -- --         CH.sub.3                                                                          Br   H H     OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-1                                                                               0  H   H   -- --         H  OCH.sub.3                                                                           H H     Cl  OCH.sub.3                                                                          CH                     L-4 Q-1                                                                               0  H   H   -- --         H  F    H H     CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-1                                                                               0  H   H   -- --         Cl Br   H H     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-1                                                                               0  H   H   -- --         Cl CH.sub.3                                                                            H H     CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-1                                                                               0  H   H   -- --         F  CH.sub.3                                                                            H H     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-1                                                                               0  H   H   -- --         H  Cl   Cl                                                                               H     CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-1                                                                               0  H   H   -- --         H  CH.sub.3                                                                            F H     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-1                                                                               0  H   CH.sub.3                                                                           -- --         H  H    H H     Cl  OCH.sub.3                                                                          CH                     L-4 Q-1                                                                               0  CH.sub.3                                                                           H      --         H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-1                                                                               1  H   H      --         F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-1                                                                               1  H   H      --         H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               0  H   H      --         H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-2                                                                               0  H   H      --         H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4 Q-2                                                                               0  H   H      --         H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               0  H   H      --         Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-2                                                                               0  H   H      --         F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               0  H   H      --         H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               0  H   H      --         F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-2                                                                               0  H   H      --         Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-2                                                                               0  H   H      --         H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4 Q-2                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               1  H   H      --         H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-2                                                                               1  H   H      --         Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-2                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               0  H   H      CH.sub.3   H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-3                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               0  H   H      CH.sub.3   Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               0  H   H      CH.sub.3   F  F    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-3                                                                               0  H   H      CH.sub.3   H  Br   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-3                                                                               0  H   H      CH.sub.3   CH.sub.3                                                                          H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-3                                                                               0  H   H      CH.sub.3   H  OCH.sub.3                                                                           --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               0  H   H      CH.sub.3   H  F    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               0  H   H      CH.sub.3   Cl Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               0  H   H      CH.sub.3   Cl CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-3                                                                               0  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               0  H   H      CH.sub.3   Cl Cl   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-3                                                                               0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               0  H   CH.sub.3                                                                              CH.sub.3   H  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               0  CH.sub.3                                                                           H      CH.sub.3   H  H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-3                                                                               1  H   H      CH.sub.3   F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-3                                                                               1  H   H      CH.sub.3   H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-4                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-4                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-4                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4 Q-4                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-4                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-4                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-5                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               0  H   H      --         F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-5                                                                               0  H   H      --         H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-5                                                                               0  H   H      --         CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-5                                                                               0  H   H      --         H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               0  H   H      --         H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               0  H   H      --         Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               0  H   H      --         Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-5                                                                               0  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-5                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               0  H   CH.sub.3                                                                              --         H  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               0  CH.sub.3                                                                           H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-5                                                                               1  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-5                                                                               1  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-6                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4 Q-6                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-6                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-6                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               0  H   H      --         H  CH.sub. 3                                                                           --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               0  H   H      --         H  CH.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-6                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4 Q-6                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-6                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-6                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-7                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               0  H   H      --         F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-7                                                                               0  H   H      --         H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-7                                                                               0  H   H      --         CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-7                                                                               0  H   H      --         H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               0  H   H      --         H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               0  H   H      --         Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               0  H   H      --         Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-7                                                                               0  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-7                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               0  H   CH.sub.3                                                                              --         H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               0  CH.sub.3                                                                           H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-7                                                                               1  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-7                                                                               1  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-8                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4 Q-8                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-8                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-8                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               0  H   H      --         H  CH.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-8                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4 Q-8                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-8                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-8                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-9                                                                               0  H   H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-9                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-9                                                                               0  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-9                                                                               0  H   H      CH.sub.3   F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-9                                                                               0  H   H      CH.sub.3   H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-9                                                                               0  H   H      CH.sub.3   CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-9                                                                               0  H   H      CH.sub.3   H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-9                                                                               0  H   H      CH.sub.3   H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-9                                                                               0  H   H      CH.sub.3   Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-9                                                                               0  H   H      CH.sub.3   Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-9                                                                               0  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.                                                                           CH                     L-4 Q-9                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-4 Q-9                                                                               0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-9                                                                               0  H   CH.sub.3                                                                              CH.sub.3   H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-9                                                                               0  CH.sub.3                                                                           H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-9                                                                               1  H   H      CH.sub.3   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-9                                                                               1  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.                                                                           CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-4 Q-10                                                                              0  H   H      CH.sub.3   F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-10                                                                              0  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-4 Q-10                                                                              0  H   H      CH.sub.3   H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-4 Q-10                                                                              0  H   OCH.sub.3                                                                             CH.sub.3   H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-4 Q-10                                                                              0  CH.sub.3                                                                           Cl     CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-10                                                                              1  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-4 Q-10                                                                              1  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-4 Q-10                                                                              1  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-1                                                                               0  H   H      --         H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-1                                                                               0  H   H      --         H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-1                                                                               0  H   H      --         Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-1                                                                               0  H   H      --         F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5 Q-1                                                                               0  H   H      --         H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-1                                                                               0  H   H      --         CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-1                                                                               0  H   H      --         H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-1                                                                               0  H   H      --         H  F    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-1                                                                               0  H   H      --         Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-1                                                                               0  H   H      --         Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-1                                                                               0  H   H      --         F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-1                                                                               0  H   H      --         H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5 Q-1                                                                               0  H   H      --         H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-1                                                                               0  H   CH.sub.3                                                                              --         H  H    H H  -- Cl  OCH.sub.                                                                           CH                     L-5 Q-1                                                                               0  CH.sub.3                                                                           H      --         H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-1                                                                               1  H   H      --         F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-1                                                                               1  H   H      --         H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               0  H   H      --         H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-2                                                                               0  H   H      --         H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5 Q-2                                                                               0  H   H      --         H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               0  H   H      --         Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-2                                                                               0  H   H      --         F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               0  H   H      --         H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               0  H   H      --         F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-2                                                                               0  H   H      --         Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-2                                                                               0  H   H      --         H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5 Q-2                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               1  H   H      --         H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-2                                                                               1  H   H      --         Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-2                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               0  H   H      CH.sub.3   H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-3                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               0  H   H      CH.sub.3   Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               0  H   H      CH.sub.3   F  F    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5 Q-3                                                                               0  H   H      CH.sub.3   H  Br   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-3                                                                               0  H   H      CH.sub.3   CH.sub.3                                                                          H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-3                                                                               0  H   H      CH.sub.3   H  OCH.sub.3                                                                           --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               0  H   H      CH.sub.3   H  F    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               0  H   H      CH.sub.3   Cl Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               0  H   H      CH.sub.3   Cl CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-3                                                                               0  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5 Q-3                                                                               0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               0  H   CH.sub.3                                                                              CH.sub.3   H  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               0  CH.sub.3                                                                           H      CH.sub.3   H  H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-3                                                                               1  H   H      CH.sub.3   F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-3                                                                               1  H   H      CH.sub.3   H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-4                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-4                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-4                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5 Q-4                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-4                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-4                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-5                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-5                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-5                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-5                                                                               0  H   H      --         F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5 Q-5                                                                               0  H   H      --         H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-5                                                                               0  H   H      --         CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-5                                                                               0  H   H      --         H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-5                                                                               0  H   H      --         Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-5                                                                               0  H   H      --         Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-5                                                                               0  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-5                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5 Q-5                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-5                                                                               0  H   CH.sub.3                                                                              --         H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-5                                                                               0  CH.sub.3                                                                           H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-5                                                                               1  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-5                                                                               1  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-6                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5 Q-6                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-6                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-6                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-6                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5 Q-6                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-6                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-6                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-7                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               0  H   H      --         F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.                                                                            N                      L-5 Q-7                                                                               0  H   H      --         H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-7                                                                               0  H   H      --         CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-7                                                                               0  H   H      --         H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               0  H   H      --         H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               0  H   H      --         Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               0  H   H      --         Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-7                                                                               0  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5 Q-7                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.                                                                           OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               0  H   CH.sub.3                                                                              --         H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               0  CH.sub.3                                                                           H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-7                                                                               1  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-7                                                                               1  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-8                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5 Q-8                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-8                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.                                                                           CH                     L-5 Q-8                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-8                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-8                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5 Q-8                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5 Q-8                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-8                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-8                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               0  H   H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-9                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               0  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               0  H   H      CH.sub.3   F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5 Q-9                                                                               0  H   H      CH.sub.3   H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-9                                                                               0  H   H      CH.sub.3   CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-9                                                                               0  H   H      CH.sub.3   H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               0  H   H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               0  H   H      CH.sub.3   Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               0  H   H      CH.sub.3   Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-9                                                                               0  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-5 Q-9                                                                               0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               0  H   CH.sub.3                                                                              CH.sub.3   H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               0  CH.sub.3                                                                           H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-9                                                                               1  H   H      CH.sub.3   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-9                                                                               1  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-5 Q-10                                                                              0  H   H      CH.sub.3   F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-10                                                                              0  H   H      CH.sub.2 CH.sub.3                                                                         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-5 Q-10                                                                              0  H   H      CH.sub.3   H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              0  H   OCH.sub.3                                                                             CH.sub.3   H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-5 Q-10                                                                              0  CH.sub.3                                                                           Cl     CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              1  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-5 Q-10                                                                              1  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-5 Q-10                                                                              1  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               0  H   H      --         H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-1                                                                               0  H   H      --         H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               0  H   H      --         Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               0  H   H      --         F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-1                                                                               0  H   H      --         H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-1                                                                               0  H   H      --         CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-1                                                                               0  H   H      --         H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               0  H   H      --         H  F    H H  -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               0  H   H      --         Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               0  H   H      --         Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-1                                                                               0  H   H      --         F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               0  H   H      --         H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-1                                                                               0  H   H      --         H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               0  H   CH.sub.3                                                                              --         H  H    H H  -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               0  CH.sub.3                                                                           H      --         H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-1                                                                               1  H   H      --         F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-1                                                                               1  H   H      --         H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               0  H   H      --         H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-2                                                                               0  H   H      --         H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-6 Q-2                                                                               0  H   H      --         H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               0  H   H      --         Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-2                                                                               0  H   H      --         F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               0  H   H      --         H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               0  H   H      --         F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-2                                                                               0  H   H      --         Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-2                                                                               0  H   H      --         H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6 Q-2                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               1  H   H      --         H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-2                                                                               1  H   H      --         Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-2                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               0  H   H      CH.sub.3   H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-3                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               0  H   H      CH.sub.3   Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               0  H   H      CH.sub.3   F  F    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-3                                                                               0  H   H      CH.sub.3   H  Br   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-3                                                                               0  H   H      CH.sub.3   CH.sub.3                                                                          H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-3                                                                               0  H   H      CH.sub.3   H  OCH.sub.3                                                                           --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               0  H   H      CH.sub.3   H  F    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               0  H   H      CH.sub.3   Cl Br   --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               0  H   H      CH.sub.3   Cl CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-3                                                                               0  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-3                                                                               0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               0  H   CH.sub.3                                                                              CH.sub.3   H  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               0  CH.sub.3                                                                           H      CH.sub.3   H  H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-3                                                                               1  H   H      CH.sub.3   F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-3                                                                               1  H   H      CH.sub.3   H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-6 Q-4                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-4                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-4                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-4                                                                               0  H   H      --         H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6 Q-4                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-4                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-4                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-5                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               0  H   H      --         F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-5                                                                               0  H   H      --         H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-5                                                                               0  H   H      --         CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-5                                                                               0  H   H      --         H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               0  H   H      --         H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               0  H   H      --         Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               0  H   H      --         Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-5                                                                               0  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-5                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               0  H   CH.sub.3                                                                              --         H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               0  CH.sub.3                                                                           H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-5                                                                               1  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-5                                                                               1  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-6                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-6 Q-6                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-6                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-6                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-6                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6 Q-6                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-6                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-6                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-7                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-7                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-7                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-7                                                                               0  H   H      --         F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-7                                                                               0  H   H      --         H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-7                                                                               0  H   H      --         CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-7                                                                               0  H   H      --         H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-7                                                                               0  H   H      --         H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 O-7                                                                               0  H   H      --         Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-7                                                                               0  H   H      --         Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-7                                                                               0  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-7                                                                               0  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-7                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-7                                                                               0  H   CH.sub.3                                                                              --         H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-7                                                                               0  CH.sub.3                                                                           H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-7                                                                               1  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-7                                                                               1  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               0  H   H      --         H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-8                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                     L-6 Q-8                                                                               0  H   H      --         H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               0  H   H      --         Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-8                                                                               0  H   H      --         F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               0  H   H      --         H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               0  H   H      --         F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-8                                                                               0  H   H      --         Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               0  H   H      --         H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               0  H   H      --         CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               0  H   H      --         H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-8                                                                               0  H   H      --         H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               0  H   OCH.sub.3                                                                             --         H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6 Q-8                                                                               0  CH.sub.3                                                                           Cl     --         F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               1  H   H      --         H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-8                                                                               1  H   H      --         Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-8                                                                               1  H   H      --         F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               0  H   H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-9                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               0  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               0  H   H      CH.sub.3   F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-9                                                                               0  H   H      CH.sub.3   H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-9                                                                               0  H   H      CH.sub.3   CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-9                                                                               0  H   H      CH.sub.3   H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               0  H   H      CH.sub.3   H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               0  H   H      CH.sub.2 CH.sub.3                                                                         Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               0  H   H      CH.sub.2 CH.sub.3                                                                         Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-9                                                                               0  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               0  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                      L-6 Q-9                                                                               0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               0  H   CH.sub.3                                                                              CH.sub.3   H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               0  CH.sub.3                                                                           OCH.sub.3                                                                             CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-9                                                                               1  H   H      CH.sub.3   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-9                                                                               1  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-10                                                                              0  H   H      CH.sub.3   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              0  H   H      CH.sub.3   Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                      L-6 Q-10                                                                              0  H   H      CH.sub.3   F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              0  H   H      CH.sub.3   F  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              0  H   H      CH.sub.3   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-10                                                                              0  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              0  H   H      CH.sub.3   H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              0  H   H      CH.sub.3   CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              0  H   H      CH.sub.3   H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                     L-6 Q-10                                                                              0  H   H      CH.sub.3   H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              0  H   OCH.sub.3                                                                             CH.sub.3   H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                      L-6 Q-10                                                                              0  CH.sub.3                                                                           Cl     CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              0  CH.sub.3                                                                           Cl     CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              1  H   H      CH.sub.3   H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                     L-6 Q-10                                                                              1  H   H      CH.sub.3   Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                      L-6 Q-10                                                                              1  H   H      CH.sub.3   F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                     __________________________________________________________________________

                                      TABLE IIA                                    __________________________________________________________________________     General Structure II (wherein R.sub.12 is OH and R.sub.13 is H)                                                            m.p.                               L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                          R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  (°C.)                       __________________________________________________________________________     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  F    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  CH.sub.3                                                                           --                                                                               H  H    H H  -- Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 CH.sub.3                                                                          H   --                                                                               H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-2                                                                               1 H  H   --                                                                               F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                     L-2                                                                               Q-2                                                                               1 H  H   --                                                                               Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  OCH.sub.3                                                                          --                                                                               H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                                     L-2                                                                               Q-2                                                                               1 CH.sub.3                                                                          Cl  --                                                                               F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    __________________________________________________________________________

                                      TABLE IIB                                    __________________________________________________________________________     General Structure II (wherein R.sub.12 is OCH.sub.3 and R.sub.13 is H)                                                     m.p.                               L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                          R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  (°C.)                       __________________________________________________________________________     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  F    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  CH.sub.3                                                                           --                                                                               H  H    H H  -- Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 CH.sub.3                                                                          H   --                                                                               H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-1                                                                               1 H  H   --                                                                               F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-1                                                                               1 H  H   --                                                                               H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                     L-2                                                                               Q-2                                                                               1 H  H   --                                                                               F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                     L-2                                                                               Q-2                                                                               1 H  H   --                                                                               Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                                    L-2                                                                               Q-2                                                                               1 H  H   --                                                                               H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                    L-2                                                                               Q-2                                                                               1 H  OCH.sub.3                                                                          --                                                                               H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                                     L-2                                                                               Q-2                                                                               1 CH.sub.3                                                                          Cl  --                                                                               F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                                    __________________________________________________________________________

                                      TABLE IIC                                    __________________________________________________________________________     General Structure II (wherein R.sub.12 is OH and R.sub.13 is H)                                                                 m.p.                          L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                          R.sub.3                                                                             R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  (°C.)                  __________________________________________________________________________     L-2                                                                               Q-4                                                                               1 H  H   --     H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                                L-2                                                                               Q-4                                                                               1 H  H   --     H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-2                                                                               Q-4                                                                               1 H  H   --     CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                L-2                                                                               Q-4                                                                               1 H  H   --     H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-2                                                                               Q-4                                                                               1 H  H   --     F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                                L-2                                                                               Q-4                                                                               1 H  H   --     H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  CH.sub.3                                                                           --     H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 CH.sub.3                                                                          H   --     H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-2                                                                               Q-4                                                                               1 H  H   --     F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-2                                                                               Q-4                                                                               1 H  H   --     F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                L-2                                                                               Q-4                                                                               1 H  H   --     Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                               L-2                                                                               Q-4                                                                               1 H  H   --     H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-2                                                                               Q-4                                                                               1 H  OCH.sub.3                                                                          --     H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                                L-2                                                                               Q-4                                                                               1 CH.sub.3                                                                          Cl  --     F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-4                                                                               Q-1                                                                               1 CH.sub.3                                                                          H     --   H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-4                                                                               Q-1                                                                               1 H  H     --   F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-4                                                                               Q-1                                                                               1 H  H     --   H  H    H H  -- OCH.sub. 3                                                                         OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  H     --   H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                               L-4                                                                               Q-2                                                                               1 H  H     --   H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                               L-4                                                                               Q-2                                                                               1 H  H     --   H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  H     --   Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-4                                                                               Q-2                                                                               1 H  H     --   F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  H     --   H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  H     --   F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                L-4                                                                               Q-2                                                                               1 H  H     --   Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  H     --   H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  H     --   CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  H     --   H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                               L-4                                                                               Q-2                                                                               1 H  H     --   H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  OCH.sub.3                                                                            --   H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                                L-4                                                                               Q-2                                                                               1 CH.sub.3                                                                          Cl    --   F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  H     --   H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-4                                                                               Q-2                                                                               1 H  H     --   Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                L-4                                                                               Q-2                                                                               1 H  H     --   F  CH.sub.3                                                                            --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                               L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                               L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            F  F    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                                L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            H  Br   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            CH.sub.3                                                                          H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                                L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            H  OCH.sub.3                                                                           --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                               L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            H  F    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            Cl Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            Cl CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            F  CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-4                                                                               Q-3                                                                               1 H  H     CH.sub.3                                                                            Cl Cl   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                                L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                               L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                L-5                                                                               Q-10                                                                              1 H  H     CH.sub.2 CH.sub.3                                                                   Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                               L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-5                                                                               Q-10                                                                              1 H  OCH.sub.3                                                                            CH.sub.3                                                                            H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                                L-5                                                                               Q-10                                                                              1 CH.sub.3                                                                          Cl    CH.sub.3                                                                            F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                L-5                                                                               Q-10                                                                              1 H  H     CH.sub.3                                                                            F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                               L-6                                                                               Q-1                                                                               1 H  H     --   H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                               L-6                                                                               Q-1                                                                               1 H  H     --   H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                               L-6                                                                               Q-1                                                                               1 H  H     --   Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-6                                                                               Q-1                                                                               1 H  H     --   F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                L-6                                                                               Q-1                                                                               1 H  H     --   H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-6                                                                               Q-1                                                                               1 H  H     --   CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                                L-6                                                                               Q-1                                                                               1 H  H     --   H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                               L-6                                                                               Q-1                                                                               1 H  H     --   H  F    H H  -- CH.sub.3                                                                           Cl  CH                               L-6                                                                               Q-1                                                                               1 H  H     --   Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-6                                                                               Q-1                                                                               1 H  H     --   Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-6                                                                               Q-1                                                                               1 H  H     --   F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-6                                                                               Q-1                                                                               1 H  H     --   H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                                L-6                                                                               Q-1                                                                               1 H  H     --   H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-6                                                                               Q-1                                                                               1 H  CH.sub.3                                                                             --   H  H    H H  -- Cl  OCH.sub.3                                                                          CH                               L-6                                                                               Q-1                                                                               1 CH.sub.3                                                                          H     --   H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                                L-6                                                                               Q-1                                                                               1 H  H     --   F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-6                                                                               Q-1                                                                               1 H  H     --   H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                               L-6                                                                               Q-2                                                                               1 H  H     --   H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                               L-6                                                                               Q-2                                                                               1 H  H     --   H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                               __________________________________________________________________________

                                      TABLE IID                                    __________________________________________________________________________     General Structure IIa (where R.sub.12 and R.sub.13 are H)                                                                            m.p.                     L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                           R.sub.3                                                                               R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                             R.sub.10                                                                         R.sub.11                                                                          X   Y   Z  (°C.)             __________________________________________________________________________     L-2                                                                               Q-1                                                                               0 H  H   --        H  H    H    H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-2                                                                               Q-1                                                                               0 H  H   --        H  Cl   H    H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-1                                                                               0 H  H   --        Cl Cl   H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-1                                                                               0 H  H   --        F  F    H    H -- CH.sub.3                                                                           CH.sub.3                                                                           N                           L-2                                                                               Q-1                                                                               0 H  H   --        H  Br   H    H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-1                                                                               0 H  H   --        CH.sub.3                                                                          H    H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-2                                                                               Q-1                                                                               0 H  H   --        H  OCH.sub.3                                                                           H    H -- Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-1                                                                               0 H  H   --        H  F    H    H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-1                                                                               0 H  H   --        Cl Br   H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-1                                                                               0 H  H   --        Cl CH.sub.3                                                                            H    H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-1                                                                               0 H  H   --        F  CH.sub.3                                                                            H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-1                                                                               0 H  H   --        H  Cl   Cl   H -- CH.sub.3                                                                           CH.sub.3                                                                           N                           L-2                                                                               Q-1                                                                               0 H  H   --        H  CH.sub.3                                                                            F    F -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-1                                                                               0 H  CH.sub.3                                                                           --        H  H    H    H -- Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-1                                                                               0 CH.sub.3                                                                          H   --        H  H    H    H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-1                                                                               1 H  H   --        F  F    H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-1                                                                               1 H  H   --        H  H    H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               0 H  H   --        H  H    --   --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-2                                                                               Q-2                                                                               0 H  H   --        H  H    --   --                                                                               H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                          L-2                                                                               Q-2                                                                               0 H  H   --        H  H    --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               0 H  H   --        Cl H    --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-2                                                                               0 H  H   --        F  H    --   --                                                                               H  Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               0 H  H   --        H  Br   --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               0 H  H   --        F  F    --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-2                                                                               Q-2                                                                               0 H  H   --        Cl Cl   --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               0 H  H   --        H  CH.sub.3                                                                            --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               0 H  H   --        CH.sub.3                                                                          CH.sub.3                                                                            --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               0 H  H   --        H  CO.sub.2 CH.sub.3                                                                   --   --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-2                                                                               Q-2                                                                               0 H  H   --        H  F    --   --                                                                               CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               0 H  OCH.sub.3                                                                          --        H  Cl   --   --                                                                               H  OCH.sub.3                                                                          CH.sub.3                                                                           N                           L-2                                                                               Q-2                                                                               0 CH.sub.3                                                                          Cl  --        F  CH.sub.3                                                                            --   --                                                                               CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               1 H  H      --     H  Cl   --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-2                                                                               1 H  H      --     Cl Cl   --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-2                                                                               Q-2                                                                               1 H  H      --     F  CH.sub.3                                                                            --   --                                                                               H  Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              H  H    --   --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              H  Cl   --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              Cl Cl   --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              F  F    --   --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           N                           L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              H  Br   --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              CH.sub.3                                                                          H    --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              H  OCH.sub.3                                                                           --   --                                                                               H  Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              H  F    --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              Cl Br   --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              Cl CH.sub.3                                                                            --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              F  CH.sub.3                                                                            --   --                                                                               CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              H  Cl   --   --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           N                           L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                              H  CH.sub.3                                                                            --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               0 H  CH.sub.3                                                                              CH.sub.3                                                                              H  H    --   --                                                                               H  Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               0 CH.sub.3                                                                          H      CH.sub.3                                                                              H  H    --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-3                                                                               1 H  H      CH.sub.3                                                                              F  F    --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-3                                                                               1 H  H      CH.sub.3                                                                              H  H    --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-4                                                                               0 H  H      --     H  H    --   --                                                                               -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-2                                                                               Q-4                                                                               0 H  H      --     H  H    --   --                                                                               -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                          L-2                                                                               Q-4                                                                               0 H  H      --     H  H    --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-4                                                                               0 H  H      --     Cl H    --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-4                                                                               0 H  H      --     F  H    --   --                                                                               -- Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-4                                                                               0 H  H      --     H  Br   --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-4                                                                               0 H  H      --     F  F    --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-2                                                                               Q-4                                                                               0 H  H      --     Cl Cl   --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-4                                                                               0 H  H      --     H  CH.sub.3                                                                            --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-4                                                                               0 H  H      --     CH.sub.3                                                                          CH.sub.3                                                                            --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-4                                                                               0 H  H      --     H  CO.sub.2 CH.sub.3                                                                   --   --                                                                               -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-2                                                                               Q-4                                                                               0 H  H      --     H  F    --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-4                                                                               0 H  OCH.sub.3                                                                             --     H  Cl   --   --                                                                               -- OCH.sub.3                                                                          CH.sub.3                                                                           N                           L-2                                                                               Q-8                                                                               0 H  H      --     H  CO.sub.2 CH.sub.3                                                                   --   --                                                                               -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-2                                                                               Q-8                                                                               0 H  H      --     H  F    --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-8                                                                               0 H  OCH.sub.3                                                                             --     H  Cl   --   --                                                                               -- OCH.sub.3                                                                          CH.sub.3                                                                           N                           L-2                                                                               Q-8                                                                               0 CH.sub.3                                                                          Cl     --     F  CH.sub.3                                                                            --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-8                                                                               1 H  H      --     H  Cl   --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-8                                                                               1 H  H      --     Cl Cl   --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-2                                                                               Q-8                                                                               1 H  H      --     F  CH.sub.3                                                                            --   --                                                                               -- Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              H  H    --   --                                                                               -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              H  Cl   --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              Cl Cl   --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              F  F    --   --                                                                               -- CH.sub.3                                                                           CH.sub.3                                                                           N                           L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              H  Br   --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              CH.sub.3                                                                          H    --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              H  OCH.sub.3                                                                           --   --                                                                               -- Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              H  F    --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              Cl Br   --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              Cl CH.sub.3                                                                            --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              F  CH.sub.3                                                                            --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              H  Cl   --   --                                                                               -- CH.sub.3                                                                           CH.sub.3                                                                           N                           L-2                                                                               Q-9                                                                               0 H  H      CH.sub.3                                                                              H  CH.sub.3                                                                            --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               0 H  CH.sub.3                                                                              CH.sub.3                                                                              H  H    --   --                                                                               -- Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               0 CH.sub.3                                                                          H      CH.sub.3                                                                              H  H    --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-9                                                                               1 H  H      CH.sub.3                                                                              F  F    --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-9                                                                               1 H  H      CH.sub.3                                                                              H  H    --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-10                                                                              0 H  H      CH.sub.3                                                                              H  H    --   --                                                                               -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-2                                                                               Q-10                                                                              0 H  H      CH.sub.3                                                                              H  H    --   --                                                                               -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                          L-2                                                                               Q-10                                                                              0 H  H      CH.sub.3                                                                              H  H    --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-10                                                                              0 H  H      CH.sub.3                                                                              Cl H    --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-2                                                                               Q-10                                                                              0 H  H      CH.sub.3                                                                              F  H    --   --                                                                               -- Cl  OCH.sub.3                                                                          CH                          L-2                                                                               Q-10                                                                              0 H  H      CH.sub.3                                                                              H  Br   --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-2                                                                               Q-10                                                                              0 H  H      CH.sub.3                                                                              F  F    --   --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-2                                                                               Q-10                                                                              0 H  H      CH.sub.3                                                                              Cl Cl   --   --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  H  H    H    H -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  H  Cl   H    H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  Cl Cl   H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  F  F    H    H -- CH.sub.3                                                                           CH.sub.3                                                                           N                           L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  H  Br   H    H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  CH.sub.3                                                                          H    H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  H  OCH.sub.3                                                                           H    H -- Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  H  F    H    H -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  Cl Br   H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  Cl CH.sub.3                                                                            H    H -- CH.sub.3                                                                           CH.sub.3                                                                           N                           L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  F  CH.sub.3                                                                            H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  H  Cl   Cl   H -- CH.sub.3                                                                           CH.sub.3                                                                           N                           L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3  H  CH.sub.3                                                                            F    F -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               0 H  CH.sub.3                                                                           CH.sub.3  H  H    H    H -- Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               0 CH.sub.3                                                                          H   CH.sub.3  H  H    H    H -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-1                                                                               1 H  H   CH.sub.3  F  F    H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-1                                                                               1 H  H   CH.sub.3  H  H    H    H -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3  H  H    --   --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3  H  H    --   --                                                                               H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3  H  H    --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3  Cl H    --   --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3  F  H    --   --                                                                               H  Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3  H  Br   --   --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          --     F  F         --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          --     Cl Cl        --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          --     H  CH.sub.3  --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          --     CH.sub.3                                                                          CH.sub.3  --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          --     H  CO.sub.2 CH.sub.3                                                                        --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                          --     H  F         --                                                                               CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               0 H  OCH.sub.3                                                                          CH.sub.3                                                                          --     H  Cl        --                                                                               H  OCH.sub.3                                                                          CH.sub.3                                                                           N                           L-3                                                                               Q-2                                                                               0 CH.sub.3                                                                          Cl  CH.sub.3                                                                          --     F  CH.sub.3  --                                                                               CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               1 H  H   CH.sub.3                                                                          --     H  Cl        --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-2                                                                               1 H  H   CH.sub.3                                                                          --     Cl Cl        --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-3                                                                               Q-2                                                                               1 H  H   CH.sub.3                                                                          --     F  CH.sub.3  --                                                                               H  Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  H         --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  Cl        --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               0 H  H   CH.sub. 3                                                                         CH.sub.3                                                                              Cl Cl        --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              F  F         --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           N                           L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  Br        --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              CH.sub.3                                                                          H         --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  OCH.sub.3 --                                                                               H  Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  F         --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              Cl Br        --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              Cl CH.sub.3  --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              F  CH.sub.3  --                                                                               CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                     H  Cl        --                                                                               H  CH.sub.3                                                                           CH.sub.3                                                                           N                           L-3                                                                               Q-3                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  CH.sub.3  --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          CH.sub.3                                                                              H  H         --                                                                               H  Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          CH.sub.3                                                                              H  H         --                                                                               H  CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                          CH.sub.3                                                                              F  F         --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-3                                                                               1 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  H         --                                                                               H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          --     H  H         --                                                                               -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          --     H  H         --                                                                               -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                          L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          --     H  H         --                                                                               -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                          --     Cl H         --                                                                               -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     H  H    --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     H  H    --     -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                          L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     H  H    --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     Cl H    --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     F  H    --     -- Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     H  Br   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     F  F    --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     Cl Cl   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     H  CH.sub.3                                                                            --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     CH.sub.3                                                                          CH.sub.3                                                                            --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     CH.sub.3                                                                          CO.sub.2 CH.sub.3                                                                   --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-3                                                                               Q-8                                                                               0 H  H   CH.sub.3                                                                          --     H  F    --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-8                                                                               0 H  OCH.sub.3                                                                          CH.sub.3                                                                          --     H  Cl   --     -- OCH.sub.3                                                                          CH.sub.3                                                                           N                           L-3                                                                               Q-8                                                                               0 CH.sub.3                                                                          Cl  CH.sub.3                                                                          --     F  CH.sub.3                                                                            --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-8                                                                               1 H  H   CH.sub.3                                                                          --     H  Cl   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-8                                                                               1 H  H   CH.sub.3                                                                          --     Cl Cl   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-3                                                                               Q-8                                                                               1 H  H   CH.sub.3                                                                          --     F  CH.sub.3                                                                            --     -- Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  H    --     -- CH.sub.3                                                                           CH.sub.3                                                                           CH                          L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  Cl   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-9                                                                               0 H  H   CH.sub. 3                                                                         CH.sub.3                                                                              Cl Cl   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              F  F    --     -- CH.sub.3                                                                           CH.sub.3                                                                           N                           L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  Br   --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              CH.sub.3                                                                          H    --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                           L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  OCH.sub.3                                                                           --     -- Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  F    --     -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                          L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              Cl Br   --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              Cl CH.sub.3                                                                            --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              F  CH.sub.3                                                                            --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.3                                                                              H  Cl   --     -- CH.sub.3                                                                           CH.sub.3                                                                           N                           L-3                                                                               Q-9                                                                               0 H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                     H  CH.sub.3                                                                            --     -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                          L-3                                                                               Q-9                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                     H  H    --     -- Cl  OCH.sub.3                                                                          CH                          L-3                                                                               Q-9                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                          CH.sub.2 CH.sub.2 CH.sub.3                                                            H  H    --     -- CH.sub.3                                                                           OCH.sub.3                                                                          N                           __________________________________________________________________________

                                      TABLE IIE                                    __________________________________________________________________________     General Structure IIb (wherein R.sub.12 and R.sub.13 are H)                                                                      m.p.                         L  Q.sub.1                                                                           n R  R.sub.1                                                                            R.sub.2                                                                           R.sub.3                                                                             R.sub.7                                                                           R.sub.8                                                                             R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X   Y   Z  (°C.)                 __________________________________________________________________________     L-2                                                                               Q-1                                                                               0 H  H   --      H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-2                                                                               Q-1                                                                               0 H  H   --      H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  H   --      Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  H   --      F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                               L-2                                                                               Q-1                                                                               0 H  H   --      H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-1                                                                               0 H  H   --      CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-2                                                                               Q-1                                                                               0 H  H   --      H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  H   --      H  F    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  H   --      Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  H   --      Cl CH.sub.3                                                                            H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-1                                                                               0 H  H   --      F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  H   --      H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                               L-2                                                                               Q-1                                                                               0 H  H   --      H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  CH.sub.3                                                                           --      H  H    H H  -- Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 CH.sub.3                                                                          H   --      H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-1                                                                               1 H  H   --      F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               1 H  H   --      H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-2                                                                               0 H  H   --      H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-2                                                                               Q-2                                                                               0 H  H   --      H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                              L-2                                                                               Q-2                                                                               0 H  H   --      H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-2                                                                               0 H  H   --      Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-2                                                                               0 H  H   --      F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-2                                                                               0 H  H   --      H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-2                                                                               0 H  H   --      F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-2                                                                               Q-2                                                                               0 H  H   --      Cl Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-2                                                                               0 H  H   --      H  CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-2                                                                               0 H  H   --      CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-2                                                                               0 H  H   --      H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-2                                                                               Q-2                                                                               0 H  H   --      H  F    --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-2                                                                               0 H  OCH.sub.3                                                                          --      H  Cl   --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           N                               L-2                                                                               Q-2                                                                               0 CH.sub.3                                                                          Cl  --      F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  H   --      H  OH   --                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-2                                                                               Q-1                                                                               0 H  H      --   H  OH   --                                                                               H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  H      --   H  OH   --                                                                               H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-1                                                                               0 H  H      --   H  OH   --                                                                               H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-1                                                                               0 H  H      --   H  OH   --                                                                               H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-2                                                                               Q-1                                                                               0 H  H      --   H  OH   --                                                                               H  -- Cl  OCH.sub.3                                                                          N                               L-2                                                                               Q-2                                                                               1 H  H      --   H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-2                                                                               1 H  H      --   Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-2                                                                               Q-2                                                                               1 H  H      --   F  CH.sub.3                                                                            --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            H  Cl   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            Cl Cl   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            F  F    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                               L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            H  Br   --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            CH.sub.3                                                                          H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            H  OCH.sub.3                                                                           --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            H  F    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            Cl Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            Cl CH.sub.3                                                                            --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            F  CH.sub.3                                                                            --                                                                               -- CH.sub.3                                                                          OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            H  Cl   --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           N                               L-2                                                                               Q-3                                                                               0 H  H      CH.sub.3                                                                            H  CH.sub.3                                                                            --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               0 H  CH.sub.3                                                                              CH.sub.3                                                                            H  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               0 CH.sub.3                                                                          H      CH.sub.3                                                                            H  H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-3                                                                               1 H  H      CH.sub.3                                                                            F  F    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-3                                                                               1 H  H      CH.sub.3                                                                            H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-4                                                                               0 H  H      --   H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-2                                                                               Q-4                                                                               0 H  H      --   H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                              L-2                                                                               Q-4                                                                               0 H  H      --   H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-4                                                                               0 H  H      --   Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-4                                                                               0 H  H      --   F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-4                                                                               0 H  H      --   H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-4                                                                               0 H  H      --   F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-2                                                                               Q-4                                                                               0 H  H      --   Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub. 3                                                                         CH                              L-2                                                                               Q-4                                                                               0 H  H   --      H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-4                                                                               0 H  H   --      CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-4                                                                               0 H  H   --      H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-2                                                                               Q-4                                                                               0 H  H   --      H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-4                                                                               0 H  OCH.sub.3                                                                          --      H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                               L-2                                                                               Q-4                                                                               0 CH.sub.3                                                                          Cl  --      F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-4                                                                               1 H  H   --      H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-4                                                                               1 H  H   --      Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-2                                                                               Q-4                                                                               1 H  H   --      F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               0 H  H   --      H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-2                                                                               Q-5                                                                               0 H  H   --      H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               0 H  H   --      Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               0 H  H   --      F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                               L-2                                                                               Q-5                                                                               0 H  H   --      H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-5                                                                               0 H  H   --      CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-2                                                                               Q-5                                                                               0 H  H   --      H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               0 H  H   --      H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               0 H  H   --      Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               0 H  H   --      Cl CH.sub. 3                                                                           --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-5                                                                               0 H  H   --      F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               0 H  H   --      H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                               L-2                                                                               Q-5                                                                               0 H  H   --      H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               0 H  CH.sub.3                                                                           --      H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               0 CH.sub.3                                                                          H   --      H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-5                                                                               1 H  H   --      F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-5                                                                               1 H  H   --      H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-6                                                                               0 H  H   --      H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-2                                                                               Q-6                                                                               0 H  H   --      H  H    --                                                                               -- -- OCH.sub. 3                                                                         CH.sub.3                                                                           CH                              L-2                                                                               Q-6                                                                               0 H  H   --      H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-6                                                                               0 H  H   --      Cl H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-2                                                                               Q-6                                                                               0 H  H   --      F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                              L-2                                                                               Q-6                                                                               0 H  H   --      H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-6                                                                               0 H  H   --      F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-2                                                                               Q-6                                                                               0 H  H   --      Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-6                                                                               0 H  H   --      H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-2                                                                               Q-6                                                                               0 H  H   --      CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-2                                                                               Q-6                                                                               0 H  H   --      H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- Cl  CH.sub.3                                                                           CH                              L-2                                                                               Q-6                                                                               0 H  H   --      H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               H  H    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               H  Cl   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               Cl Cl   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               F  F    H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                               L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               H  Br   H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               CH.sub.3                                                                          H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               H  OCH.sub.3                                                                           H H  -- Cl  OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               H  F    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               Cl Br   H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               Cl CH.sub. 3                                                                           H H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                               L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               F  CH.sub.3                                                                            H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               H  Cl   Cl                                                                               H  -- CH.sub.3                                                                           CH.sub.3                                                                           N                               L-3                                                                               Q-1                                                                               0 H  H   CH.sub.3                                                                               H  CH.sub.3                                                                            F F  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                               H  H    H H  -- Cl  OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                               H  H    H H  -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-3                                                                               Q-1                                                                               1 H  H   CH.sub.3                                                                               F  F    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-1                                                                               1 H  H   CH.sub.3                                                                               H  H    H H  -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                               H  H    --                                                                               -- H  CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          CH.sub.3                                                                           CH                              L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                               H  H    --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                               Cl H    --                                                                               -- H  CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                               F  H    --                                                                               -- H  Cl  OCH.sub.3                                                                          CH                              L-3                                                                               Q-2                                                                               0 H  H   CH.sub.3                                                                               H  Br   --                                                                               -- H  OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                               F  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                              L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                               H  Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                               F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                               Cl Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                               H  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                               CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                               H  CO.sub.2 CH.sub.3                                                                   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-3                                                                               Q-4                                                                               0 H  H   CH.sub.3                                                                               H  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-4                                                                               0 H  OCH.sub.3                                                                          CH.sub.3                                                                               H  Cl   --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           N                               L-3                                                                               Q-4                                                                               0 CH.sub.3                                                                          Cl  CH.sub.3                                                                               F  CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-4                                                                               1 H  H   CH.sub.3                                                                               H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-4                                                                               1 H  H   CH.sub.3                                                                               Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-3                                                                               Q-4                                                                               1 H  H   CH.sub.3                                                                               F  CH.sub.3                                                                            --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               H  Cl   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               Cl Cl   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               F  F    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                               L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               H  Br   --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               CH.sub.3                                                                          H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               H  OCH.sub.3                                                                           --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               H  F    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               Cl Br   --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               Cl CH.sub.3                                                                            --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               F  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               H  Cl   --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           N                               L-3                                                                               Q-5                                                                               0 H  H   CH.sub.3                                                                               H  CH.sub.3                                                                            --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               0 H  CH.sub.3                                                                           CH.sub.3                                                                               H  H    --                                                                               -- -- Cl  OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               0 CH.sub.3                                                                          H   CH.sub.3                                                                               H  H    --                                                                               -- -- CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-3                                                                               Q-5                                                                               1 H  H   CH.sub.3                                                                               F  F    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-5                                                                               1 H  H   CH.sub.3                                                                               H  H    --                                                                               -- -- OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-6                                                                               0 H  H   CH.sub.3                                                                               H  H    --                                                                               -- -- CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-3                                                                               Q-6                                                                               0 H  H   CH.sub.3                                                                               H  H    --                                                                               -- -- OCH.sub.3                                                                          CH.sub.3                                                                           CH                              L-3                                                                               Q-9                                                                               1 H  H   CH.sub.3                                                                          CH.sub.3                                                                            F  F    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-9                                                                               1 H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                   H  H    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub. 3                                                                         CH.sub.3                                                                            H  H    --                                                                               --    CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            H  H    --                                                                               --    OCH.sub.3                                                                          CH.sub.3                                                                           CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            H  H    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            Cl H    --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          N                               L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            F  H    --                                                                               --    Cl  OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            H  Br   --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            F  F    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            Cl Cl   --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            H  CH.sub.3                                                                            --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            CH.sub.3                                                                          CH.sub.3                                                                            --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            H  CO.sub.2 CH.sub.3                                                                   --                                                                               --    CH.sub.3                                                                           CH.sub.3                                                                           CH                              L-3                                                                               Q-10                                                                              0 H  H   CH.sub.3                                                                          CH.sub.3                                                                            H  F    --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              0 H  OCH.sub.3                                                                          CH.sub.3                                                                          CH.sub.3                                                                            H  Cl   --                                                                               --    OCH.sub.3                                                                          CH.sub.3                                                                           N                               L-3                                                                               Q-10                                                                              0 CH.sub.3                                                                          Cl  CH.sub.3                                                                          CH.sub.3                                                                            F  CH.sub.3                                                                            --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                   H  Cl   --                                                                               --    CH.sub.3                                                                           OCH.sub.3                                                                          CH                              L-3                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                          CH.sub.3                                                                            Cl Cl   --                                                                               --    OCH.sub.3                                                                          OCH.sub.3                                                                          N                               L-3                                                                               Q-10                                                                              1 H  H   CH.sub.3                                                                          CH.sub.2 CH.sub.3                                                                   F  CH.sub.3                                                                            --                                                                               --    Cl  OCH.sub.3                                                                          CH                              __________________________________________________________________________

                                      TABLE III                                    __________________________________________________________________________     General Structure III (wherein R.sub.12 and R.sub.13 are H)                                                                                m.p.               A  Q n R R.sub.1                                                                        R.sub.                                                                            R.sub.7                                                                           R.sub.8                                                                           R.sub.9                                                                          R.sub.10                                                                          R.sub.11                                                                          X.sub.1                                                                             Y.sub.1                                                                           Y.sub.2                                                                           X.sub.2                                                                            Y.sub.3                                                                             X.sub.3                                                                           X.sub.4                                                                            Y.sub.4                                                                            Z  (°C.)       __________________________________________________________________________     A-2 Q-1                                                                             0 H H                                                                              -- H  H  H H  -- CH.sub.3                                                                            O  -- --  --   --                               A-2 Q-1                                                                             0 H H                                                                              -- H  H  H H  -- CH.sub.3                                                                            CH.sub.2                                                                          -- --  --   --                               A-2 Q-1                                                                             0 H H                                                                              -- H  H  H H  -- OCH.sub.3                                                                           O  -- --  --   --                               A-2 Q-5                                                                             0 H H                                                                              -- H  H  --                                                                               -- -- CH.sub.3                                                                            CH.sub.2                                                                          -- --  --   --                               A-2 Q-2                                                                             0 H H                                                                              -- H  Cl --                                                                               -- H  OCF.sub.2 H                                                                         O  -- --  --   --                               A-3 Q-1                                                                             0 H H                                                                              -- H  H  H H  -- CH.sub.3                                                                            -- -- --  --   --                               A-3 Q-1                                                                             0 H H                                                                              -- H  H  H H  -- OCH.sub.3                                                                           -- -- --  --   --                               A-3 Q-1                                                                             0 H H                                                                              -- H  F  H Cl -- OCF.sub.2 H                                                                         -- -- --  --   --                               A-3 Q-1                                                                             1 H H                                                                              -- Cl Cl H H  -- CH.sub.3                                                                            -- -- --  --   --                               A-3 Q-1                                                                             0 H H                                                                              -- CH.sub.3                                                                          H  H H  -- OCH.sub.3                                                                           -- -- --  --   --                               A-3 Q-4                                                                             0 H H                                                                              -- H  H  --                                                                               -- -- OCH.sub.3                                                                           -- -- --  --   --                               A-3 Q-3                                                                             0 H H                                                                              CH.sub.3                                                                          H  CH.sub.3                                                                          --                                                                               -- H  CH.sub.3                                                                            -- -- --  --   --                               A-4 Q-1                                                                             0 H H                                                                              -- H  H  H H  -- CH.sub.3                                                                            -- H  --  --   --                               A-4 Q-1                                                                             0 H H                                                                              -- H  Cl H H  -- OCH.sub.3                                                                           -- H  --  --   --                               A-4 Q-1                                                                             1 H H                                                                              -- F  F  Cl                                                                               CH.sub.3                                                                          -- CH.sub.3                                                                            -- CH.sub.3                                                                          --  --   --                               A-4 Q-6                                                                             0 H H                                                                              -- H  H  --                                                                               -- -- OCH.sub.3                                                                           -- H  --  --   --                               A-4 Q-7                                                                             0 H H                                                                              -- CH.sub.3                                                                          F  --                                                                               -- -- CH.sub.3                                                                            -- CH.sub.3                                                                          --  --   --                               A-5 Q-1                                                                             0 H H                                                                              -- H  H  H H  -- --   -- -- CH.sub.3                                                                           CH.sub.3                                                                            --                               A-5 Q-1                                                                             0 H H                                                                              -- Cl H  H Cl -- --   -- -- OCH.sub.3                                                                          CH.sub.3                                                                            --                               A-5 Q-10                                                                            0 H H                                                                              CH.sub.3                                                                          H  H  --                                                                               -- -- --   -- -- CH.sub.3                                                                           CH.sub.2 CF.sub.3                                                                   --                               A-6 Q-1                                                                             0 H H                                                                              -- H  H  H H  -- --   -- -- --  --   CH.sub.3                         A-7 Q-1                                                                             0 H H  H  H  H H  --                        CH.sub.3                                                                           CH.sub.3                                                                           CH                    A-7 Q-1                                                                             0 H H  H  H  H H  --                        CH.sub.3                                                                           OCH.sub.3                                                                          N                     A-7 Q-2                                                                             0 H H  H  H  --                                                                               -- H                         CH.sub.3                                                                           OCH.sub.3                                                                          CH                    A-7 Q-2                                                                             0 H H  H  H  --                                                                               -- H                         OCH.sub.3                                                                          OCH.sub.3                                                                          N                     A-7 Q-4                                                                             0 H H  H  H  --                                                                               -- --                        OCH.sub.3                                                                          OCH.sub.3                                                                          CH                    A-7 Q-4                                                                             0 H H  H  H  --                                                                               -- --                        CH.sub.3                                                                           CH.sub.3                                                                           N                     __________________________________________________________________________

                                      TABLE IV                                     __________________________________________________________________________     General Structure IV                                                           L  Q  A  R.sub.1                                                                           R.sub.2                                                                           R.sub.3                                                                           R.sub.7                                                                           R.sub.8                                                                           R.sub.9                                                                           R.sub.10                                                                          R.sub.11                                                                          X.sub.1                                                                              Y.sub.1                                                                           Y.sub.2                                                                           X.sub.2                                                                            Y.sub.3                                                                           X.sub.3                                                                            m.p. (°         __________________________________________________________________________                                                             C.)                    L-2                                                                               Q-1                                                                               A-2                                                                               H  -- -- H  H  H  H  -- CH.sub.3                                                                             O  -- --  -- --                         L-2                                                                               Q-6                                                                               A-4                                                                               H  -- -- H  Cl -- -- -- OCH.sub.3                                                                            -- H  --  -- --                         L-2                                                                               Q-10                                                                              A-5                                                                               H  -- CH.sub.3                                                                          H  H  -- -- -- --    -- -- OCH.sub.3                                                                          CH.sub.3                                                                          --                         L-3                                                                               Q-1                                                                               A-3                                                                               H  CH.sub.3                                                                          -- H  H  H  H  -- OCH.sub.3                                                                            -- -- --  -- --                         L-3                                                                               Q-1                                                                               A-6                                                                               H  CH.sub.3                                                                          -- Cl H  H  H  -- --    -- -- --  -- OCH.sub.3                  L-3                                                                               Q-3                                                                               A-2                                                                               H  CH.sub.3                                                                          CH.sub.3                                                                          H  H  -- -- H  OCH.sub.3                                                                            CH.sub.2                                                                          -- --  -- --                         L-4                                                                               Q-1                                                                               A-3                                                                               H  -- -- H  H  H  H  -- OCH.sub.3                                                                            -- -- --  -- --                         L-4                                                                               Q-1                                                                               A-4                                                                               H  -- -- H  F  H  H  -- OCH.sub.3                                                                            -- CH.sub.3                                                                          --  -- --                         L-4                                                                               Q-2                                                                               A-2                                                                               H  -- -- H  CH.sub.3                                                                          -- -- H  OCF.sub.2 H                                                                          O  -- --  -- --                         L-4                                                                               Q-3                                                                               A-4                                                                               H  -- CH.sub.3                                                                          H  H  -- -- H  CH.sub.3                                                                             -- CH.sub.3                                                                          --  -- --                         L-5                                                                               Q-1                                                                               A-2                                                                               H  -- -- H  H  H  H  -- OCH.sub.2 CH.sub.3                                                                   CH.sub.2                                                                          -- --  -- --                         L-5                                                                               Q-1                                                                               A-6                                                                               H  -- -- H  Cl H  H  -- --    -- -- --  -- CH.sub.3                   L-5                                                                               Q-4                                                                               A-2                                                                               H  -- -- H  H  -- -- -- OCH.sub.3                                                                            O  -- --  -- --                         L-5                                                                               Q-7                                                                               A-5                                                                               H  -- -- H  H  -- -- -- --    -- -- SCH.sub.3                                                                          CH.sub.3                                                                          --                         L-6                                                                               Q-1                                                                               A-2                                                                               H  -- -- H  H  H  H  -- CH.sub.3                                                                             O  -- --  -- --                         L-6                                                                               Q-5                                                                               A-2                                                                               H  -- -- H  CH.sub.3                                                                          -- -- -- CH.sub.3                                                                             CH.sub.2                                                                          -- --  -- --                         L-6                                                                               Q-8                                                                               A-6                                                                               H  -- -- H  H  -- -- -- --    -- -- --  -- OCH.sub.3                  L-6                                                                               Q-9                                                                               A-2                                                                               H  -- CH.sub.3                                                                          H  H  -- -- -- OCH.sub.3                                                                            O  -- --  -- --                         L-2                                                                               Q-1                                                                               A-2                                                                               H  -- -- H  OH -- -- -- OCH.sub.3                                                                            O  -- --  -- --                         __________________________________________________________________________

                                      TABLE V                                      __________________________________________________________________________     General Structure V (where R.sub.9 and R.sub.10 are a carbonyl group)          L  Q  R  R.sub.1                                                                          R.sub.2                                                                           R.sub.7                                                                           R.sub.8                                                                               X   Y   Z  m.p.(°C.)                            __________________________________________________________________________     L-1                                                                               Q-1                                                                               H  H -- H  H      CH.sub.3                                                                           CH.sub.3                                                                           CH                                             L-1                                                                               Q-1                                                                               H  H -- H  H      OCH.sub.3                                                                          CH.sub.3                                                                           CH                                             L-1                                                                               Q-1                                                                               H  H -- H  H      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                             L-1                                                                               Q-1                                                                               H  H -- H  H      CH.sub.3                                                                           CH.sub.3                                                                           N                                              L-1                                                                               Q-1                                                                               H  H -- H  H      OCH.sub.3                                                                          CH.sub.3                                                                           N                                              L-1                                                                               Q-1                                                                               H  H -- H  H      OCH.sub.3                                                                          OCH.sub.3                                                                          N                                              L-1                                                                               Q-1                                                                               H  H -- H  Cl     CH.sub.3                                                                           OCH.sub.3                                                                          CH                                             L-1                                                                               Q-1                                                                               H  H -- H  F      CH.sub.3                                                                           OCH.sub.3                                                                          N                                              L-1                                                                               Q-1                                                                               H  H -- H  Br     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                             L-1                                                                               Q-1                                                                               H  H -- H  CN     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                             L-1                                                                               Q-1                                                                               H  H -- H  CH.sub.3                                                                              CH.sub.3                                                                           OCH.sub. 3                                                                         N                                              L-1                                                                               Q-1                                                                               H  H -- H  OCH.sub.3                                                                             CH.sub.3                                                                           CH.sub.3                                                                           CH                                             L-1                                                                               Q-1                                                                               H  H -- H  CO.sub.2 CH.sub.3                                                                     OCH.sub.3                                                                          OCH.sub.3                                                                          N                                              L-1                                                                               Q-1                                                                               H  H -- H  SO.sub.2 N(CH.sub.3).sub.2                                                            CH.sub.3                                                                           OCH.sub.3                                                                          CH                                             L-1                                                                               Q-1                                                                               H  H -- H  SCH.sub.3                                                                             CH.sub.3                                                                           OCH.sub.3                                                                          CH                                             L-1                                                                               Q-1                                                                               H  H -- H  SO.sub.2 CH.sub.3                                                                     CH.sub.3                                                                           CH.sub.3                                                                           N                                              L-1                                                                               Q-1                                                                               CH.sub.3                                                                          H -- H  H      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                             L-2                                                                               Q-1                                                                               H  H -- H  H      CH.sub.3                                                                           OCH.sub.3                                                                          CH                                             L-2                                                                               Q-1                                                                               H  H -- H  H      OCH.sub.3                                                                          OCH.sub.3                                                                          N                                              L-3                                                                               Q-1                                                                               H  H CH.sub.3                                                                          H  H      OCH.sub.3                                                                          CH.sub.3                                                                           CH                                             L-3                                                                               Q-1                                                                               H  H CH.sub.3                                                                          H  H      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                             L-4                                                                               Q-1                                                                               H  H -- H  H      CH.sub.3                                                                           OCH.sub.3                                                                          N                                              L-4                                                                               Q-1                                                                               H  H -- H  CH.sub.3                                                                              CH.sub.3                                                                           OCH.sub.3                                                                          CH                                             L-5                                                                               Q-1                                                                               H  H -- H  H      OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                             L-5                                                                               Q-1                                                                               H  H -- H  Cl     CH.sub.3                                                                           CH.sub.3                                                                           CH                                             L-6                                                                               Q-1                                                                               H  H -- H  H      OCH.sub.3                                                                          OCH.sub.3                                                                          N                                              L-6                                                                               Q-1                                                                               H  H -- H  H      CH.sub.3                                                                           CH.sub.3                                                                           N                                              L-6                                                                               Q-1                                                                               H  H -- Cl Cl     OCH.sub.3                                                                          OCH.sub.3                                                                          CH                                             __________________________________________________________________________

Formulations

Useful formulations of the compounds of Formula I can be prepared in conventional ways. They include dusts, granules, pellets, solutions, suspensions, emulsions, wettable powders, emulsifiable concentrates and the like. Many of these may be applied directly. Sprayable formulations can be extended in suitable media and used at spray volumes of from a few liters to several hundred liters per hectare. High strength compositions are primarily used as intermediates for further formulations. The formulations, broadly, contain about 0.1% to 99% by weight of active ingredient(s) and at least one of (a) about 0.1% to 20% surfactant(s) and (b) about 1% to 99.9% solid or liquid inert diluent(s). More specifically, they will contain these ingredients in the following approximate proportions:

    ______________________________________                                                     Weight Percent*                                                                Active                                                                         Ingredient                                                                             Diluent(s)                                                                               Surfactant(s)                                    ______________________________________                                         Wettable Powders                                                                             20-90      0-74     1-10                                         Oil Suspensions,                                                                              3-50     40-95     0-15                                         Emulsions, Solutions,                                                          (including Emulsifiable                                                        Concentrates)                                                                  Aqueous Suspension                                                                           10-50     40-84     1-20                                         Dusts          1-25     70-99     0-5                                          Granules and Pellets                                                                         0.1-95      5-99.9  0-15                                         High Strength 90-99      0-10     0-2                                          Compositions                                                                   ______________________________________                                          *Active ingredient plus at least one of a Surfactant or a Diluent equals       100 weight percent.                                                      

Lower or higher levels of active ingredient can, of course, be present depending on the intended use and the physical properties of the compound. Higher ratios of surfactant to active ingredient are sometimes desirable, and are achieved by incorporation into the formulation or by tank mixing.

Typical solid diluents are described in Watkins, et al., "Handbook of Insecticide Dust Diluents and Carriers", 2nd Ed., Dorland Books, Caldwell, N.J., but other solids, either mined or manufactured, may be used. The more absorptive diluents are preferred for wettable powders and the denser ones for dusts. Typical liquid diluents and solvents are described in Marsden, "Solvents Guide," 2nd Ed., Interscience, New York, 1950. Solubility under 0.1% is preferred for suspension concentrates; solution concentrates are preferably stable against phase separation at 0° C. "McCutcheon's Detergents and Emulsifiers Annual", MC Publishing Corp., Ridgewood, N.J., as well as Sisely and Wood, "Encyclopedia of Surface Active Agents", Chemical Publishing Co., Inc., New York, 1964, list surfactants and recommended uses. All formulations can contain minor amounts of additives to reduce foaming, caking, corrosion, microbiological growth, etc.

The methods of making such compositions are well known. Solutions are prepared by simply mixing the ingredients. Fine solid compositions are made by blending and, usually, grinding as in a hammer or fluid energy mill. Suspensions are prepared by wet milling (see, for example, Littler, U.S. Pat. No. 3,060,084). Granules and pellets may be made by spraying the active material upon preformed granular carriers or by agglomeration techniques. See J. E. Browning, "Agglomeration", Chemical Engineering, Dec. 4, 1967, pp. 147ff. and "Perry's Chemical Engineer's Handbook", 5th Ed., McGraw-Hill, New York, 1973, pp. 8-57ff.

For further information regarding the art of formulation, see for example:

H. M. Loux, U.S. Pat. No. 3,235,361, Feb. 15, 1966, Col. 6, line 16 through Col. 7, line 19 and Examples 10 through 41;

R. W. Luckenbaugh, U.S. Pat. No. 3,309,192, Mar. 14, 1967, Col. 5, line 43 through Col. 7, line 62 and Examples 8, 12, 15, 39, 41, 52, 53, 58, 132, 138-140, 162-164, 166, 167 and 169-182;

H. Gysin and E. Knusli, U.S. Pat. No. 2,891,855, June 23, 1959, Col. 3, line 66 through Col. 5, line 17 and Examples 1-4;

G. C. Klingman, "Weed Control as a Science", John Wiley and Sons, Inc., New York, 1961, pp. 81-96; and

J. D. Fryer and S. A. Evans, "Weed Control Handbook", 5th Ed., Blackwell Scientific Publications, Oxford, 1968, pp. 101-103.

In the following examples, all parts are by weight unless otherwise indicated.

EXAMPLE 8 Wettable Powder

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranylmethyl)benzenesulfonamide: 50%

sodium alkylnaphthalenesulfonate: 2%

low viscosity methyl cellulose: 2%

diatomaceous earth: 46%

The ingredients are blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in diameter. The product is reblended before packaging.

EXAMPLE 9 Granule

Wettable Powder of Example 8: 5%

attapulgite granules (U.S.S. 20-40 mesh; 0.84-0.42 mm): 95%

A slurry of wettable powder containing 25% solids is sprayed on the surface of attapulgite granules in a double-cone blender. The granules are dried and packaged.

EXAMPLE 10 Extruded Pellet

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranylmethyl)benzenesulfonamide: 25%

anhydrous sodium sulfate: 10%

crude calcium ligninsulfonate: 5%

sodium alkylnaphthalenesulfonate: 1%

calcium/magnesium bentonite: 59%

The ingredients are blended, hammer-milled and then moistened with about 12% water. The mixture is extruded as cylinders about 3 mm diameter which are cut to produce pellets about 3 mm long. These may be used directly after drying, or the dried pellets may be crushed to pass a U.S.S. No. 20 sieve (0.84 mm openings). The granules held on a U.S.S. No. 40 sieve (0.42 mm openings) may be packaged for use and the fines recycled.

EXAMPLE 11 Low Strength Granule

2-(2,2-dichlorocyclopropyl)-N-[(4-methoxy-6-methyl)aminocarbonyl]benzenesulfonamide: 1%

N,N-dimethylformamide: 9%

attapulgite granules (U.S.S. 20-40 sieve): 90%

The active ingredient is dissolved in the solvent and the solution is sprayed upon dedusted granules in a double cone blender. After spraying of the solution has been completed, the blender is allowed to run for a short period and then the granules are packaged.

EXAMPLE 12 Aqueous Suspension

2-(2,2-dichlorocyclopropyl)-N-[(4-methoxy-6-methyl)aminocarbonyl]benzenesulfonamide: 40%

polyacrylic acid thickener: 0.3%

dodecylphenol polyethylene glycol ether: 0.5%

disodium phosphate: 1%

monosodium phosphate: 0.5%

polyvinyl alcohol: 1.0%

water: 56.7%

The ingredients are blended and ground together in a sand mill to produce particles essentially all under 5 microns in size.

EXAMPLE 13 Oil Suspension

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranylmethyl)benzenesulfonamide: 35%

blend of polyalcohol carboxylic esters and oil soluble petroleum sulfonates: 6%

xylene: 59%

The ingredients are combined and ground together in a sand mill to produce particles essentially all below 5 microns. The product can be used directly, extended with oils, or emulsified in water.

EXAMPLE 14 Granule

2-(2,2-dichlorocyclopropyl)-N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]benzenesulfonamide: 80%

wetting agent: 1%

crude ligninsulfonate salt (containing 5-20% of the natural sugars): 10%

attapulgite clay: 9%

The ingredients are blended and milled to pass through a 100 mesh screen. This material is then added to a fluid bed granulator, the air flow is adjusted to gently fluidize the material, and a fine spray of water is sprayed onto the fluidized material. The fluidization and spraying are continued until granules of the desired size range are made. The spraying is stopped, but fluidization is continued, optionally with heat, until the water content is reduced to the desired level, generally less than 1%. The material is then discharged, screened to the desired size range, generally 14-100 mesh (1410-149 microns), and packaged for use.

EXAMPLE 15 High Strength Concentrate

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranylmethyl)benzenesulfonamide: 99%

silica aerogel: 0.5%

synthetic amorphous silica: 0.5%

The ingredients are blended and ground in a hammer-mill to produce a material essentially all passing a U.S.S. No. 50 screen (0.3 mm opening). The concentrate may be formulated further if necessary.

EXAMPLE 16 Wettable Powder

2-(2,2-dichlorocyclopropyl)-N-[(4-methoxy-6-methyl)aminocarbonyl]benzenesulfonamide: 90%

dioctyl sodium sulfosuccinate: 0.1%

synthetic fine silica: 9.9%

The ingredients are blended and ground in a hammer-mill to produce particles essentially all below 100 microns. The material is sifted through a U.S.S. No. 50 screen and then packaged.

EXAMPLE 17 Wettable Powder

2-(2,2-dichlorocyclopropyl)-N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]benzenesulfonamide: 40%

sodium ligninsulfonate: 20%

montmorillonite clay: 40%

The ingredients are thoroughly blended, coarsely hammer-milled and then air-milled to produce particles essentially all below 10 microns in size. The material is reblended and then packaged.

EXAMPLE 18 Dust

N-[(4,6-dimethoxypyrimidin-2-yl)aminocarbonyl]-2-(2-oxiranylmethyl)benzenesulfonamide: 10%

attapulgite: 10%

Pyrophyllite: 80%

The active ingredient is blended with attapulgite and then passed through a hammer-mill to produce particles substantially all below 200 microns. The ground concentrate is then blended with powdered pyrophyllite until homogeneous.

Utility

Test results indicate that the compounds of the present invention are highly active preemergent or postemergent herbicides or plant growth regulants. Many of them have utility for broad-spectrum pre- and or post-emergence weed control in areas where complete control of all vegetation is desired, such as around fuel storage tanks, ammunition depots, industrial storage areas, parking lots, drive-in theaters, around billboards, highway and railroad structures. Some of the compounds have utility for selective weed control in crops such as rice and wheat. Alternatively, the subject compounds are useful to modify plant growth.

The rates of application for the compounds of the invention are determined by a number of factors, including their use as plant growth modifiers or as herbicides, the crop species involved, the types of weeds to be controlled, weather and climate, formulations selected, mode of application, amount of foliage present, etc. In general terms, the subject compounds should be applied at levels of arount 0.05 to 10 kg/ha, the lower rates being suggested for use on lighter soils and/or those having a low organic matter content, for plant growth modification or for situations where only short-term persistence is required.

The compounds of the invention may be used in combination with any other commercial herbicide, examples of which are those of the triazine, triazole, uracil, urea, amide, diphenylether, carbamate and bipyridylium types.

The herbicidal properties of the subject compounds were discovered in a number of greenhouse tests. The test procedures and results follow.

Test A

Seeds of crabgrass (Digitaria sp.), barnyardgrass (Echinochloa crusgalli), wild oats (Avena fatua), cheatgrass (Bromus secalinus), velvetleaf (Abtuilon theophrasti), sicklepod (Cassia obtusifolia), morningglory (Ipomoea sp.), cocklebur (Xanthium sp.), sorghum, corn, soybean, rice, wheat and nutsedge tubers (Cyperus rotundus) were planted in a growth medium and treated pre-emergence with the chemicals dissolved in a nonphytotoxic solvent. At the same time, cotton having five leaves (including cotyledonary ones), bush beans with the third trifoliate leaf expanding, crabgrass, barnyardgrass and wild oats with two leaves, sicklepod with three leaves (including cotyledonary ones), morningglory and cocklebur with four leaves (including the cotyledonary ones), sorghum and corn with four leaves, soybean with two cotyledonary leaves, rice with three leaves, wheat with one leaf, and nutsedge with three to five leaves were sprayed. Treated plants and controls were maintained in a greenhouse for sixteen days, whereupon all species were compared to controls and visually rated for response to treatment. The ratings are based on a numerical scale extending from 0=no injury, to 10=complete kill. The accompanying descriptive symbols have the following meanings:

C=chlorosis or necrosis;

B=burn;

D=defoilation;

E=emergence inhibition;

G=growth retardation;

H=formative effects;

U=unusual pigmentation

X=axillary stimulation;

S=albinism; and

6Y=abscised buds or flowers.

    ______________________________________                                         Compounds                                                                       ##STR52##                                                                     Compound n     Q             X     Y     Z                                     ______________________________________                                         1        0     2,2-dichloro-cyclopropyl                                                                     CH.sub.3                                                                             CH.sub.3                                                                             CH                                    2        0     2,2-dichloro-cyclopropyl                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            CH                                    3        0     2,2-dichloro-cyclopropyl                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    4        0     2,2-dichloro-cyclopropyl                                                                     CH.sub.3                                                                             CH.sub.3                                                                             N                                     5        0     2,2-dichloro-cyclopropyl                                                                     CH.sub.3                                                                             OCH.sub.3                                                                            N                                     6        0     2,2-dichloro-cyclopropyl                                                                     OCH.sub.3                                                                            OCH.sub.3                                                                            N                                     7        1                                                                                     ##STR53##    OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    8        0                                                                                     ##STR54##    OCH.sub.3                                                                            OCH.sub.3                                                                            CH                                    9        0                                                                                     ##STR55##    CH.sub.3                                                                             CH.sub.3                                                                             CH                                    ______________________________________                                    

                                      TABLE A                                      __________________________________________________________________________                    Com-        Com-        Com-        Com-  Com-                          Compound 1                                                                            pound 2                                                                             Compound 3                                                                            pound 4                                                                             Compound 5                                                                            pound 6                                                                             Compound 7                                                                            pound                                                                                pound 9               Rate (kg/ha)                                                                           0.05   0.05 0.05   0.05 0.05   0.05 0.05   0.05  0.05                  __________________________________________________________________________     POSTEMERGENCE                                                                  Morningglory                                                                           0      2C,5G                                                                               5C,8G  4C,8G                                                                               10C    10C  2C,8G  1C    0                     Cocklebur                                                                              5G     9C   9C     3C,8G                                                                               9C     10C  8H     2C,7G 2G                    Velvetleaf                                                                             2C,8G  9C   10C    4C,8H                                                                               10C    10C  --     9C    2G                    Nutsedge                                                                               0      10C  9C     0    9C     9C   10C    4C,9G 1C                    Crabgrass                                                                              0      2G   4G     0    2G     0    1C,5G  1C    0                     Barnyardgrass                                                                          0      8H   3H     0    2H     0    5C,9H  4C,9H 2C,4H                 Cheatgrass                                                                             0      2C,6G                                                                               2C,6G  0    2C     1C   --     3G    0                     Wild Oats                                                                              0      2G   0      0    0      0    2G     0     0                     Wheat   0      0    0      0    3G     0    2G     0     0                     Corn    0      2C,8H                                                                               1C,4G  0    3C,8H  3C,8H                                                                               2C,8H  2C,7H 2C,5G                 Soybean 2C,9G  4C,9G                                                                               5C,9G  2C,9G                                                                               3C,9G  4C,9G                                                                               4C,8H  3C,9G,7X                                                                             2C,2H                 Rice    5G     2C,7G                                                                               2C,6G  3G   5G     3G   4C,9G  6G    3G                    Sorghum 2H     2G   2G     0    2C,5H  2C,5H                                                                               2C,9H  2C,7H 2C,5G                 Sugar Beets                                                                            0      5G   4C,8G  5C,9G                                                                               9C     10C  9C     9C    2C,5G                 Cotton  4C,8H  5C,9G                                                                               5C,9G  4C,8H                                                                               5C,9G  9C   4C,4H  9C    1H                    Bushbean                                    5C,9G  --    --                    Cassia                                      2C,9G  --    --                    PREEMERGENCE                                                                   Morningglory                                                                           4G     8G   7G     7H   9G     8G   7G     5G    0                     Cocklebur                                                                              --     8H   9G     2C   9H     9C   9H     0     0                     Velvetleaf                                                                             2G     9G   9G     0    9G     5C,9G                                                                               --     0     0                     Nutsedge                                                                               0      9G   10E    0    4G     7G   5G     0     0                     Crabgrass                                                                              0      2G   2C,8G  0    0      0    2C     0     0                     Barnyardgrass                                                                          0      2C,9H                                                                               2C,7H  0    2C,3H  2C   4C,8H  0     0                     Cheatgrass                                                                             2G     5C,9H                                                                               5C,9H  0    5G     0    --     0     0                     Wild Oats                                                                              0      3C,8G                                                                               3G     0    2G     0    3C,6G  0     0                     Wheat   0      6G   2G     0    0      0    1C,3G  0     0                     Corn    2G     2C,9H                                                                               2C,8G  2G   4G     2C,6G                                                                               2C,8H  0     1H                    Soybean 0      4C,8H                                                                               7G     3C,2H                                                                               4C,8H  3C,8H                                                                               2C,8H  2C    1H                    Rice    3G     4C,8G                                                                               2C,8H  0    4G     3G   3C,8G  0     4G                    Sorghum 5G     4C,8H                                                                               2C,7H  0    2C,5G  2G   3C,9G  1C    2G                    Sugar Beets                                                                            5G     8G   9G     3C,5G                                                                               10E    5C,9G                                                                               9G     6G    2H                    Cotton  5G     9G   8G     5G   9G     9G   --     2G    0                     Bushbean                                    --     --    --                    Cassia                                      5C,9H  --    --                    __________________________________________________________________________ 

What is claimed is:
 1. A compound of the formula ##STR56## wherein W is O or S;R is H or CH₃ ; L is ##STR57## n is 0 or 1; R₁ is H, C₁ -C₃ alkyl, C₁ -C₃ haloalkyl, halogen, nitro, CN, C₁ -C₃ alkoxy, SO₂ NR^(I) R^(II), C₁ -C₃ alkylthio, C₁ -C₃ alkylsulfinyl, C₁ -C₃ alkylsulfonyl, CO₂ R^(III), CH₂ CN, CH₂ OCH₃ or CH₂ SCH₃ ; R^(I) is H, C₁ -C₄ alkyl, C₂ -C₃ cyanoalkyl, methoxy or ethoxy; R^(II) is H, C₁ -C₄ alkyl or C₃ -C₄ alkenyl; or R^(I) and R^(II) may be taken together as --(CH₂)₃ --, --(CH₂)₄ --, --(CH₂)₅ -- or --CH₂ CH₂ OCH₂ CH₂ --; R^(III) is C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ alkynyl, C₂ -C₄ haloalkyl, C₂ -C₃ cyanoalkyl, C₅ -C₆ cycloalkyl, C₄ -C₇ cycloalkylalkyl or C₂ -C₄ alkoxyalkyl; R₂ is C₁ -C₃ alkyl; Q is a 3- or 4-membered heterocyclic ring which contains one heteroatom selected from O, S and NR₃, or a 3- or 4-membered carbocyclic ring in which one carbon atom may optionally be in the form of a carbonyl group, or a fully-saturated 5- or 6-membered carbocyclic ring, and Q may be optionally substituted with 1-4 substituents selected from halogen, CN, OH, C₁ -C₃ alkyl, C₁ -C₃ alkoxy, C₁ -C₃ alkylthio, C₂ -C₄ alkoxycarbonyl, C₁ -C₄ alkylsulfonyl, (C₁ -C₄ alkyl)aminosulfamoyl and di(C₁ -C₄ alkyl)aminosulfamoyl; R₃ is C₁ -C₄ alkyl; R₁₂ is H or OR₁₄ ; R₁₃ is H or C₁ -C₄ alkyl; R₁₄ is H, C₁ -C₄ alkyl, C₃ -C₄ alkenyl, C₃ -C₄ haloalkenyl, C₃ -C₄ alkynyl, C₃ -C₄ haloalkynyl, C₂ -C₄ alkylcarbonyl, C(O)NR₁₅ R₁₆, C₁ -C₄ alkylsulfonyl, C₂ -C₄ alkoxyalkyl or C₂ -C₄ alkylthioalkyl; R₁₅ and R₁₆ are independently H or C₁ -C₂ alkyl; A is ##STR58## X Is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkyl, C₁ -C₄ haloalkylthio, C_(1`-C) ₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino or di(C₁ -C₃ alkyl)amino; Y is H, C₁ -C₄ alkyl, C₁ -C₄ alkoxy, C₁ -C₄ haloalkoxy, C₁ -C₄ haloalkylthio, C₁ -C₄ alkylthio, C₂ -C₅ alkoxyalkyl, C₂ -C₅ alkoxyalkoxy, amino, C₁ -C₃ alkylamino, di(C₁ -C₃ alkyl)amino, C₃ -C₄ alkenyloxy, C₃ -C₄ alkynyloxy, C₂ -C₅ alkylthioalkyl, C₂ -C₅ alkylsulfinylalkyl, C₂ -C₅ alkylsulfonylalkyl, C₁ -C₄ haloalkyl, C₃ -C₅ cycloalkyl, C₂ -C₄ alkynyl, ##STR59## or N(OCH₃)CH₃ ; m is 2 or 3; L₁ and L₂ are independently O or S; R₄ and R₅ are independently C₁ -C₂ alkyl; R₆ is H or CH₃ ; Z is N;and their agriculturally suitable salts; provided that (a) X or Y is other than OCF₂ H; (b) when L is L-2 or L-3, then the Q substituent and the sulfonylurea bridge are on adjacent carbon atoms; (c) when W is S, then R is H, A is A-1, and Y is CH₃, OCH₃, OC₂ H₅, CH₂ OCH₃, C₂ H₅, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, OCH₂ CH₂ OCH₃ or CH(OCH₃)₂ ; (d) the total number of carbon atoms of R₁₂ and R₁₃ must be less than or equal to four; and (e) when the total number of carbon atoms of X and Y is greater than four, then the number of carbons of R₁ must be less than or equal to two and the number of carbons of Q must be less than or equal to six.
 2. The compounds of claim 1 wherein Q is ##STR60## wherein R₃ is C₁ -C₃ alkyl;R₇ is H, F, Cl, Br, CN, CH₃ or OCH₃ ; R₈ is H, F, Cl, Br, I, CN, OH, C₁ -C₃ alkyl, C₁ -C₃ alkoxy, C₂ -C₃ alkoxycarbonyl, di(C₁ -C₃ alkyl)aminosulfamoyl, C₁ -C₃ alkylthio or C₁ -C₃ alkylsulfonyl; R₉ and R₁₀ are independently H, CH₃, F, Cl or may be taken together to form C═O; and R₁₁ is H or C₁ -C₃ alkyl;provided that (a) when R₇ and R₈ are attached to the same carbon atom as in Q-1, Q-2 or Q-3, or in Q-4 through Q-10, and R₇ is OCH₃, then R₈ is other than F, Cl, Br, I or OH; and (b) when R₇ and R₈ are attached to the same carbon atom as in Q-1, Q-2 or Q-3, or in Q-4 through Q-10, and R₈ is F, Cl, Br, I or OH, then R₇ is other than OCH₃.
 3. The compounds of claim 2 whereA is A-1. W is O; and R is H.
 4. The compounds of claim 3 whereR₁ is selected from H, F, Cl, NO₂, C₁ -C₂ alkyl, C₁ -C₂ haloalkyl, C₁ -C₂ alkoxy, C₁ -C₂ alkylthio, CH₂ OCH₃ or CH₂ SCH₃ ; R₁₃ is H or CH₃ ; R₁₄ is H, C₁ -C₂ alkyl, CH₂ CH═CH₂ or CH₂ C.tbd.CH; X is CH₃, OCH₃, OC₂ H₅, CH₂ F, OCH₂ CH₂ F, OCH₂ CHF₂, OCH₂ CF₃, CF₃, CH₂ Cl or CH₂ Br; and Y is H, C₁ -C₃ alkyl, OCH₃, OC₂ H₅, CH₂ OCH₃, NHCH₃, N(OCH₃)CH₃, N(CH₃)₂, CF₃, SCH₃, OCH₂ CH═CH₂, OCH₂ C.tbd.CH, CH₂ OC₂ H₅, OCH₂ CH₂ OCH₃, CH₂ SCH₃, OCF₂ H, SCF₂ H, cyclopropyl, C.tbd.CH or C.tbd.CCH₃.
 5. The compounds of claim 4 whereL is L-1; and Q is Q-1, Q-2 or Q-4.
 6. The compounds of claim 5 where Q is Q-1.
 7. The compounds of claim 6 whereR₁ is H, Cl, CH₃, OCH₃ or SCH₃ and is not in the 4-position; R₇ is H, F, Cl, CH₃ or OCH₃ ; R₈ is H, F, Cl, CH₃ or OCH₃ ; and R₉ and R₁₀ are independently H, CH₃, F or Cl.
 8. An agriculturally suitable composition for controlling the growth or undesired vegetation which comprises an effective amount of a compound of claim 1 and at least one of the following: surfactant, solid or liquid diluent.
 9. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 2 and at least one of the following: surfactant, solid or liquid diluent.
 10. A agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 3 and at least one of the following: surfactant, solid or liquid diluent.
 11. A agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 4 and at least one of the following: surfactant, solid or liquid diluent.
 12. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 5 and at least one of the following: surfactant, solid or liquid diluent.
 13. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 6 and at least one of the following: surfactant, solid or liquid diluent.
 14. An agriculturally suitable composition for controlling the growth of undesired vegetation which comprises an effective amount of a compound of claim 7 and at least one of the following: surfactant, solid or liquid diluent.
 15. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 1. 16. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 2. 17. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 3. 18. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 4. 19. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 5. 20. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 6. 21. A method for controlling the growth of undesired vegetation which comprises applying to the locus to be protected an effective amount of a compound of claim
 7. 